Epithelial–Mesenchymal Transition - Couverture souple

Raju, Sonu; Mathew, Deepu George; Thomas, Priya

Couverture souple

ISBN 10 : 6209158315 ISBN 13 : 9786209158315

Editeur : LAP LAMBERT Academic Publishing, 2025

Synopsis

Epithelial–Mesenchymal Transition (EMT) represents a fundamental biological process in which epithelial cells lose their characteristic polarity, intercellular adhesion, and organized architecture, acquiring a mesenchymal phenotype characterized by enhanced motility, invasiveness, and resistance to apoptosis. This reversible cellular reprogramming event plays crucial roles in embryonic development, tissue regeneration, fibrosis, and cancer progression. Over the past few decades, EMT has emerged as a pivotal paradigm in cell biology and pathology, bridging developmental processes and disease mechanisms through the regulation of cellular plasticity. Understanding the molecular, cellular, and signaling dynamics of EMT has therefore become essential for comprehending a wide spectrum of physiological and pathological phenomena.In embryogenesis, EMT governs key morphogenetic events such as gastrulation, neural crest formation, and organ development. The transient and tightly regulated conversion of epithelial cells into migratory mesenchymal cells facilitates tissue remodeling and spatial patterning necessary for the formation of complex multicellular structures.

Détails de l'édition

• Éditeur: LAP LAMBERT Academic Publishing
• Date d'édition: 2025
• Langue: anglais
• ISBN 10: 6209158315
• ISBN 13: 9786209158315
• Reliure: Broché
• Nombre de pages: 60
• Coordonnées du fabricant: non disponible
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