Analysis of Lisinopril and Tranexamic acid Tablets - Couverture souple

Raza, Asad

Couverture souple

ISBN 10 : 6209682847 ISBN 13 : 9786209682841

Editeur : LAP Lambert Academic Publishing, 2026

Synopsis

Two simple, fast, accurate and sensitive spectrophotometric methods are described for the determination of Lisinopril and Tranexamic acid in pharmaceutical preparations. The first method is based on the reaction of ninhydrin with primary amine present in Lisinopril in the presence of DMF solvent. The reaction produces a bluish green color, which absorbs maximally at 600 nm. Beer's law was obeyed in the concentration range of 10-150 ¿g/ml with molar absorptivity of 4.083 × 103 Lmole-1cm-1 While second method is based on the reaction of ninhydrin with primary amine of Tranexamic acid in the basic medium at pH.8.The reaction produces a blue color which absorb maximally at 565 nm. Beer's law was obeyed in the concentration range of 3-40 ¿g/ml with molar absorptivity of 5.093 × 103 Lmole-1cm-1.The effects of variables such as temperature, heating time, reagent concentration and stability of color were investigated to optimize the procedures. The results are valid statistically. The proposed methods have been applied to determine lisinopril and tranexamic acid in pharmaceutical preparations with good results.

Détails de l'édition

• Éditeur: LAP Lambert Academic Publishing
• Date d'édition: 2026
• Langue: anglais
• ISBN 10: 6209682847
• ISBN 13: 9786209682841
• Reliure: Broché
• Nombre de pages: 124
• Coordonnées du fabricant: non disponible
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