Mechanosensitivity of the Heart - Couverture rigide

Couverture rigide

ISBN 10 : 9048128498 ISBN 13 : 9789048128495

Editeur : Springer, 2009

Synopsis

Investigation of the mechanisms of cellular response to different mechanical stimuli, as well as mechano-electrical feedback (MEF) in the intact heart is one of the main topics in fundamental and clinical cardiology. The present volume of Mechanosensitivity in Cells and Tissues: Mechanosensitivity of the Heart c- bines excellent reviews written by worldwide leaders in this ?eld. The 3rd volume is a great addition to this excellent series of books edited by Andre Kamkin and Irina Kiseleva. This volume successfully combines reviews, aimed at academic, physiology and clinical cardiology communities, devoted to mechanosensitivity of the normal and diseased heart at the ion channel, cell, tissue and organ levels. Kamkin and Kiseleva have made signi?cant contributions to the investigation of mechanosentive ion channels in cardiomyocytes and ?broblasts. Their ba- ground, in addition to extensive collaborations helped them to ?nd and consolidate valuable research ?ndings from prominent specialists in the ?eld of cardiac mechanosensitivity. In the last decade, interest in the role of MEF in the heart has increased sign- cantly. MEF within cardiac tissue is a complex phenomenon in which electroph- iological changes are triggered by myocardial stretch. This phenomenon has been studiedintheclinicalcommunityforoveracenturyandmayhavebothpro-rhythmic and arrhythmogenic consequences. While signi?cant advances have been made in understanding of the effects of mechanical forces on cardiac cells, many questions remain regarding the mechanisms whereby mechanical forces are transduced into changes which alter the behavior of various cardiac cells.

A propos du livre

Présentation de l'éditeur

This timely review of heart mechanosensitivity examines tissues at the molecular, biological, bio-physical, physiological and pharmaceutical levels. New insight on the electromechanical properties of cardiac tissue is supported with experimental results.

Détails de l'édition

• Éditeur: Springer
• Date d'édition: 2009
• Langue: anglais
• ISBN 10: 9048128498
• ISBN 13: 9789048128495
• Reliure: Relié
• Nombre de pages: 485
• Éditeur: Kamkin Andre, Kiseleva Irina
• Coordonnées du fabricant: non disponible
• Personne responsable: Springer Nature Customer Service Center GmbH; ProductSafety@springernature.com; ; Europaplatz 3; Heidelberg; 69115; Allemagne