Principles of Cancer Genetics - Couverture souple

Bunz, Fred

 
9789048177264: Principles of Cancer Genetics

Synopsis

Cancer genetics is a field of daunting breadth and depth. The literature describes hundreds of genes and genetic alterations that are variably associated with again as many disease states and risk factors. Integrating these disparate pieces of highly specialized information is challenging for the professional scientist and student alike. This concise guidebook consolidates the main concepts of the cancer gene theory, and provides a framework for understanding the genetic basis of cancer. The book is focused on the most highly representative genes that underlie the most common cancers and highlights new frontiers in gene-based diagnosis and therapy. Primary attention is devoted to the origins of cancer genes and the application of evolutionary theory to explain why the cell clones that harbor cancer genes tend to expand.

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Présentation de l'éditeur

This concise guidebook consolidates the main concepts of the cancer gene theory, and provides a framework for understanding the genetic basis of cancer. It illuminates the integrated contributions of heredity, the environment, and acquired genetic instability.

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