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Razoxane and Dexrazoxane - Two Multifunctional Agents: Experimental and Clinical Results - Couverture rigide
Synopsis
This book provides an overview on razoxane and dexrazoxane, novel drugs with uniquely useful features. There are indications that the proteins thought to be responsible for the ravages of Alzheimer´s disease could be stabilized by one or both these drugs.
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Razoxane and Dexrazoxane - Two Multifunctional Agents (eng)
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Razoxane and Dexrazoxane - Two Multifunctional Agents
Edité par
Springer Netherlands, Springer Netherlands Okt 2010, 2010
ISBN 10 : 904819167X
ISBN 13 : 9789048191673
Neuf
Couverture rigide
Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne
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Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Razoxane and dexrazoxane are two novel drugs with some uniquely useful features. They block cell division at the G2/M border, but nowhere else, so that they have a low toxicity profile. They suppress tumor metastasis and haemorrhages through normalization of pathological blood vessels. Razoxane potentiates radiotherapy especially in the treatment of soft tissue sarcomas and gastrointestinal neoplasms.They protect normal tissues against toxic chemicals, e.g. the myocardium against anthracyclines or subcutaneous tissue against injuries caused by incidental extravasations of anthracyclines. Dexrazoxane is the only drug approved by the FDA/EMEA for the specific purpose of preventing cardiac damage when giving the widely used and effective antitumor anthracyclines. The reduction of cardiotoxicity is achieved without response reduction or reducing of time to progression of tumors. While the full analysis of their actions at the molecular level is not yet completely understood, it seems most likely that it is via an inhibition on the topoisomerase II a. Moreover, the drugs have the ability to chelate several metals including iron, copper or zinc.The protection of normal tissues is nowhere more important than that of brain, and there are indications that the proteins thought to be responsible for the ravages of Alzheimer s disease could be stabilized by one or both these drugs. 260 pp. Englisch. N° de réf. du vendeur 9789048191673
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Razoxane and Dexrazoxane - Two Multifunctional Agents
Edité par
Springer Netherlands, 2010
ISBN 10 : 904819167X
ISBN 13 : 9789048191673
Neuf
Couverture rigide
Vendeur : moluna, Greven, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Gebunden. Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Selectively summarizes the >900 publications on these drugs comprehensive overview But cites most papers Shows where lacunae areRazoxane and dexrazoxane are two novel drugs with some uniquely useful features. They block cell division at the G2/M border,. N° de réf. du vendeur 5822527
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Razoxane and Dexrazoxane - Two Multifunctional Agents : Experimental and Clinical Results
Edité par
Springer Netherlands, 2010
ISBN 10 : 904819167X
ISBN 13 : 9789048191673
Ancien ou d'occasion
Couverture rigide
Vendeur : Buchpark, Trebbin, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Etat : Sehr gut. Zustand: Sehr gut | Seiten: 260 | Sprache: Englisch | Produktart: Bücher | Razoxane and dexrazoxane are two novel drugs with some uniquely useful features. They block cell division at the G2/M border, but nowhere else, so that they have a low toxicity profile. They suppress tumor metastasis and haemorrhages through normalization of pathological blood vessels. Razoxane potentiates radiotherapy especially in the treatment of soft tissue sarcomas and gastrointestinal neoplasms. They protect normal tissues against toxic chemicals, e.g. the myocardium against anthracyclines or subcutaneous tissue against injuries caused by incidental extravasations of anthracyclines. Dexrazoxane is the only drug approved by the FDA/EMEA for the specific purpose of preventing cardiac damage when giving the widely used and effective antitumor anthracyclines. The reduction of cardiotoxicity is achieved without response reduction or reducing of time to progression of tumors. While the full analysis of their actions at the molecular level is not yet completely understood, it seems most likely that it is via an inhibition on the topoisomerase II a. Moreover, the drugs have the ability to chelate several metals including iron, copper or zinc.The protection of normal tissues is nowhere more important than that of brain, and there are indications that the proteins thought to be responsible for the ravages of Alzheimer¿s disease could be stabilized by one or both these drugs. N° de réf. du vendeur 6953303/12
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Razoxane and Dexrazoxane - Two Multifunctional Agents : Experimental and Clinical Results
Vendeur : AHA-BUCH GmbH, Einbeck, Allemagne
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Buch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - Razoxane and dexrazoxane are two novel drugs with some uniquely useful features. They block cell division at the G2/M border, but nowhere else, so that they have a low toxicity profile. They suppress tumor metastasis and haemorrhages through normalization of pathological blood vessels. Razoxane potentiates radiotherapy especially in the treatment of soft tissue sarcomas and gastrointestinal neoplasms.They protect normal tissues against toxic chemicals, e.g. the myocardium against anthracyclines or subcutaneous tissue against injuries caused by incidental extravasations of anthracyclines. Dexrazoxane is the only drug approved by the FDA/EMEA for the specific purpose of preventing cardiac damage when giving the widely used and effective antitumor anthracyclines. The reduction of cardiotoxicity is achieved without response reduction or reducing of time to progression of tumors. While the full analysis of their actions at the molecular level is not yet completely understood, it seems most likely that it is via an inhibition on the topoisomerase II a. Moreover, the drugs have the ability to chelate several metals including iron, copper or zinc.The protection of normal tissues is nowhere more important than that of brain, and there are indications that the proteins thought to be responsible for the ravages of Alzheimer s disease could be stabilized by one or both these drugs. N° de réf. du vendeur 9789048191673
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Razoxane and Dexrazoxane - Two Multifunctional Agents
Edité par
Springer, Springer Okt 2010, 2010
ISBN 10 : 904819167X
ISBN 13 : 9789048191673
Neuf
Couverture rigide
Vendeur : buchversandmimpf2000, Emtmannsberg, BAYE, Allemagne
Évaluation du vendeur 5 sur 5 étoiles
Buch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Razoxane and dexrazoxane are two novel drugs with some uniquely useful features. They block cell division at the G2/M border, but nowhere else, so that they have a low toxicity profile. They suppress tumor metastasis and haemorrhages through normalization of pathological blood vessels. Razoxane potentiates radiotherapy especially in the treatment of soft tissue sarcomas and gastrointestinal neoplasms.They protect normal tissues against toxic chemicals, e.g. the myocardium against anthracyclines or subcutaneous tissue against injuries caused by incidental extravasations of anthracyclines. Dexrazoxane is the only drug approved by the FDA/EMEA for the specific purpose of preventing cardiac damage when giving the widely used and effective antitumor anthracyclines. The reduction of cardiotoxicity is achieved without response reduction or reducing of time to progression of tumors. While the full analysis of their actions at the molecular level is not yet completely understood, it seems most likely that it is via an inhibition on the topoisomerase II a. Moreover, the drugs have the ability to chelate several metals including iron, copper or zinc.The protection of normal tissues is nowhere more important than that of brain, and there are indications that the proteins thought to be responsible for the ravages of Alzheimer¿s disease could be stabilized by one or both these drugs.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 260 pp. Englisch. N° de réf. du vendeur 9789048191673
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Razoxane and Dexrazoxane - Two Multifunctional Agents
Vendeur : Books Puddle, Woodside, NY, Etats-Unis
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Etat : New. pp. xiii + 243. N° de réf. du vendeur 261401011
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Razoxane and Dexrazoxane - Two Multifunctional Agents
impression à la demandeVendeur : Biblios, Frankfurt am main, HESSE, Allemagne
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Etat : New. PRINT ON DEMAND pp. xiii + 243. N° de réf. du vendeur 181401017
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Razoxane and Dexrazoxane - Two Multifunctional Agents
impression à la demandeVendeur : Majestic Books, Hounslow, Royaume-Uni
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Etat : New. Print on Demand pp. xiii + 243. N° de réf. du vendeur 6479724
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Razoxane and Dexrazoxane-Two Multifunctional Agents: Experimental and Clinical Results [Hardcover] [Oct 06, 2010] Rhomberg, Walter and Hellmann, Kurt
Vendeur : StainesBookhub, Weybridge, SURRE, Royaume-Uni
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Etat : New. A brand new book in pristine condition. Showing zero signs of shelf wear, creases, or damage. N° de réf. du vendeur SPRLISTINGBYSHB10268
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