This timely review of heart mechanosensitivity examines tissues at the molecular, biological, bio-physical, physiological and pharmaceutical levels. New insight on the electromechanical properties of cardiac tissue is supported with experimental results.
Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.
This timely review of heart mechanosensitivity examines tissues at the molecular, biological, bio-physical, physiological and pharmaceutical levels. New insight on the electromechanical properties of cardiac tissue is supported with experimental results.
Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.
Vendeur : Brook Bookstore On Demand, Napoli, NA, Italie
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Vendeur : moluna, Greven, Allemagne
Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. This is the first series of books that considers the problem of cell mechanosensitivity of organs and tissues at the molecular, biological, bio-physical, physiological and pharmacological levels and draws the attention to the global problem of the mechan. N° de réf. du vendeur 5826151
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Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne
Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Investigation of the mechanisms of cellular response to different mechanical stimuli, as well as mechano-electrical feedback (MEF) in the intact heart is one of the main topics in fundamental and clinical cardiology. The present volume of Mechanosensitivity in Cells and Tissues: Mechanosensitivity of the Heart c- bines excellent reviews written by worldwide leaders in this eld. The 3rd volume is a great addition to this excellent series of books edited by Andre Kamkin and Irina Kiseleva. This volume successfully combines reviews, aimed at academic, physiology and clinical cardiology communities, devoted to mechanosensitivity of the normal and diseased heart at the ion channel, cell, tissue and organ levels. Kamkin and Kiseleva have made signi cant contributions to the investigation of mechanosentive ion channels in cardiomyocytes and broblasts. Their ba- ground, in addition to extensive collaborations helped them to nd and consolidate valuable research ndings from prominent specialists in the eld of cardiac mechanosensitivity. In the last decade, interest in the role of MEF in the heart has increased sign- cantly. MEF within cardiac tissue is a complex phenomenon in which electroph- iological changes are triggered by myocardial stretch. This phenomenon has been studiedintheclinicalcommunityforoveracenturyandmayhavebothpro-rhythmic and arrhythmogenic consequences. While signi cant advances have been made in understanding of the effects of mechanical forces on cardiac cells, many questions remain regarding the mechanisms whereby mechanical forces are transduced into changes which alter the behavior of various cardiac cells. 528 pp. Englisch. N° de réf. du vendeur 9789400730892
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Taschenbuch. Etat : Neu. Mechanosensitivity of the Heart | Andre Kamkin (u. a.) | Taschenbuch | xxxvii | Englisch | 2012 | Springer | EAN 9789400730892 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. N° de réf. du vendeur 106602650
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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Molecular Mechanisms of Mechanotransduction in Cardiac Cells.- Titin and Titin-Associated Proteins in Myocardial Stress-Sensing and Mechanical Dysfunction.- Mechanical Stretch-Induced Reorganization of the Cytoskeleton and the Small GTPase Rac-1 in Cardiac Fibroblasts.- Molecular Signaling Mechanisms of Myocardial Stretch: Implications for Heart Disease.- Mechanical Stress Induces Cardiomyocyte Hypertrophy Through Agonist-Independent Activation of Angiotensin II Type 1 Receptor.- Mechanically Induced Potentials and Currents of the Cardiac Cells in Healthy and Diseased Myocardium.- Mechanostransduction in Cardiac and Stem-Cell Derived Cardiac Cells.- Stretch-Activated Channels in the Heart: Contribution to Cardiac Performance.- Effects of Applied Stretch on Native and Recombinant Cardiac Na+ Currents.- Mechanosensitive Alterations of Action Potentials and Membrane Currents in Healthy and Diseased Cardiomyocytes: Cardiac Tissue and Isolated Cell.- The Role of Mechanosensitive Fibroblasts in the Heart: Evidence from Acutely Isolated Single Cells, Cultured Cells and from Intracellular Microelectrode Recordings on Multicellular Preparations from Healthy and Diseased Cardiac Tissue.- Scanning Ion Conductance Microscopy for Imaging and Mechanosensitive Activation of Selected Areas of Live Cells.- Mechano-Electric Feedback in the Whole Heart and a Computer Simulation Study.- The Contribution of MEF to Electrical Heterogeneity and Arrhythmogenesis.- Mechanical Modulation of a Reentrant Arrhythmia: The Atrial Flutter Case.- Early Hypertrophic Signals After Myocardial Stretch. Role of Reactive Oxygen Species and the Sodium/Hydrogen Exchanger.- Stretch-Induced Inotropy in Atrial and Ventricular Myocardium.- Effects of Wall Stress on the Dynamics of Ventricular Fibrillation: A Computer Simulation Study of Mechanoelectric Feedback.- Electromechanical Modelling of Cardiac Tissue.- Arteries as a Source of Myogenic Contractile Activity: Ionic Mechanisms.- Specific Mechanotransduction Signaling Involved in Myogenic Responses of the Cerebral Arteries.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 528 pp. Englisch. N° de réf. du vendeur 9789400730892
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Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - Investigation of the mechanisms of cellular response to different mechanical stimuli, as well as mechano-electrical feedback (MEF) in the intact heart is one of the main topics in fundamental and clinical cardiology. The present volume of Mechanosensitivity in Cells and Tissues: Mechanosensitivity of the Heart c- bines excellent reviews written by worldwide leaders in this eld. The 3rd volume is a great addition to this excellent series of books edited by Andre Kamkin and Irina Kiseleva. This volume successfully combines reviews, aimed at academic, physiology and clinical cardiology communities, devoted to mechanosensitivity of the normal and diseased heart at the ion channel, cell, tissue and organ levels. Kamkin and Kiseleva have made signi cant contributions to the investigation of mechanosentive ion channels in cardiomyocytes and broblasts. Their ba- ground, in addition to extensive collaborations helped them to nd and consolidate valuable research ndings from prominent specialists in the eld of cardiac mechanosensitivity. In the last decade, interest in the role of MEF in the heart has increased sign- cantly. MEF within cardiac tissue is a complex phenomenon in which electroph- iological changes are triggered by myocardial stretch. This phenomenon has been studiedintheclinicalcommunityforoveracenturyandmayhavebothpro-rhythmic and arrhythmogenic consequences. While signi cant advances have been made in understanding of the effects of mechanical forces on cardiac cells, many questions remain regarding the mechanisms whereby mechanical forces are transduced into changes which alter the behavior of various cardiac cells. N° de réf. du vendeur 9789400730892
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Vendeur : Biblios, Frankfurt am main, HESSE, Allemagne
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