Signal Transduction in Cancer Metastasis - Couverture souple

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9789400733589: Signal Transduction in Cancer Metastasis

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ISBN 10 : 9400733585 ISBN 13 : 9789400733589

Editeur : Springer, 2012

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This book examines the signal mechanisms responsible for triggering a series of phenotypical changes of primary tumor which may lead to final colonization of the tumor in a second home. It highlights the initial stage of tumor metastasis.

Les informations fournies dans la section � Synopsis � peuvent faire r�f�rence � une autre �dition de ce titre.

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The poor prognosis and high mortality for cancer patients are majorly ascribed to tumor metastasis, one of the most complicated pathological processes. Elucidation of molecular mechanisms for metastasis is essential for management and prevention of this lethal condition. In the book to be published, we take comprehensive review in regard with the signal mechanisms responsible for triggering a series of phenotypical changes of primary tumor which may lead to final colonization of the tumor in a second home. Specifically, the initial stage of tumor metastasis will be highlighted. The complex tumor microenvironment accumulate a lot of growth factors, inflammatory cytokines and extracellular matrix which may turn into a group of potent metastatic factors. An integrated and sustained signaling induced by these metastatic factors may trigger EMT, migration and invasion of primary tumor into surround tissue. Blokcade of these signal pathways is the most effective approach for prevention of

Pr�sentation de l'�diteur

Les informations fournies dans la section � A propos du livre � peuvent faire r�f�rence � une autre �dition de ce titre.

�diteur: Springer
Date d'�dition: 2012
Langue: anglais
ISBN 10: 9400733585
ISBN 13: 9789400733589
Reliure: Broch�
Nombre de pages: 300
�diteur: Wu Wen-Sheng, Hu Chi-Tan
Coordonn�es du fabricant: GPSR Kontakt
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Signal Transduction in Cancer Metastasi (eng)

Wu, Wen-Sheng

Edit� par Springer, 2012

ISBN 10 : 9400733585 ISBN 13 : 9789400733589

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Signal Transduction in Cancer Metastasis

Chi-Tan Hu

Edit� par Springer Netherlands Dez 2012, 2012

ISBN 10 : 9400733585 ISBN 13 : 9789400733589

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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The poor prognosis and high mortality for cancer patients are majorly ascribed to tumor metastasis, one of the most complicated pathological processes. Elucidation of molecular mechanisms for metastasis is essential for management and prevention of this lethal condition. In the book to be published, we take comprehensive review in regard with the signal mechanisms responsible for triggering a series of phenotypical changes of primary tumor which may lead to final colonization of the tumor in a second home. Specifically, the initial stage of tumor metastasis will be highlighted. The complex tumor microenvironment accumulate a lot of growth factors, inflammatory cytokines and extracellular matrix which may turn into a group of potent metastatic factors. An integrated and sustained signaling induced by these metastatic factors may trigger EMT, migration and invasion of primary tumor into surround tissue. Blokcade of these signal pathways is the most effective approach for prevention of tumor metastasis. A lot of clinical trials are under way for this purpose and the outcome are promising. The expert reviews compiled in this book may encourage the researcher in this exciting field for future study. 300 pp. Englisch. N� de r�f. du vendeur 9789400733589

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Signal Transduction in Cancer Metastasis

Wu, Wen-Sheng|Hu, Chi-Tan

Edit� par Springer Netherlands, 2012

ISBN 10 : 9400733585 ISBN 13 : 9789400733589

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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Comprehensive reviews of signal transduction triggering tumor metastasis The novel mechanisms for how cross talks of different signal pathways achieveEncouraging potential clinical applications for prevention of tumor metastasisComprehensive reviews . N� de r�f. du vendeur 5826394

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Signal Transduction in Cancer Metastasis (Cancer Metastasis - Biology and Treatment, 15)

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ISBN 10 : 9400733585 ISBN 13 : 9789400733589

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Signal Transduction in Cancer Metastasis

Chi-Tan Hu

Edit� par Springer, 2012

ISBN 10 : 9400733585 ISBN 13 : 9789400733589

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Vendeur : AHA-BUCH GmbH, Einbeck, Allemagne

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Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - The poor prognosis and high mortality for cancer patients are majorly ascribed to tumor metastasis, one of the most complicated pathological processes. Elucidation of molecular mechanisms for metastasis is essential for management and prevention of this lethal condition. In the book to be published, we take comprehensive review in regard with the signal mechanisms responsible for triggering a series of phenotypical changes of primary tumor which may lead to final colonization of the tumor in a second home. Specifically, the initial stage of tumor metastasis will be highlighted. The complex tumor microenvironment accumulate a lot of growth factors, inflammatory cytokines and extracellular matrix which may turn into a group of potent metastatic factors. An integrated and sustained signaling induced by these metastatic factors may trigger EMT, migration and invasion of primary tumor into surround tissue. Blokcade of these signal pathways is the most effective approach for prevention of tumor metastasis. A lot of clinical trials are under way for this purpose and the outcome are promising. The expert reviews compiled in this book may encourage the researcher in this exciting field for future study. N� de r�f. du vendeur 9789400733589

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Signal Transduction in Cancer Metastasis

Wen-Sheng Wu (u. a.)

Edit� par Springer, 2012

ISBN 10 : 9400733585 ISBN 13 : 9789400733589

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Signal Transduction in Cancer Metastasis

Wen-Sheng Wu

Edit� par Springer, Springer Dez 2012, 2012

ISBN 10 : 9400733585 ISBN 13 : 9789400733589

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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Overview of Signal Transduction in Tumor Metastasis.- Microenvironment Triggers EMT, Migration and Invasion of Primary Tumor via Multiple Signal Pathways.- The ERK1/2 MAP Kinase Signaling Pathway in Tumor Progression and Metastasis.- Mitogen-Activated Protein Kinase-Activated Protein Kinases and Metastasis.- Grb2 and Other Adaptor Proteins in Tumor Metastasis.- The Role of ROS Signaling in Tumor Progression.- Signal Cross Talks for Sustained MAPK Activation and Cell Migration Mediated by Reactive Oxygen Species: The Involvement in Tumor Progression.- Insights into the Dynamics of Focal Adhesion Protein Trafficking in Invasive Cancer Cells and Clinical Implications.- Notch Signaling in Cancer Metastasis.- New Concepts on the Critical Functions of Cancer- and Metastasis-Initiating Cells in Treatment Resistance and Disease Relapse: Molecular Mechanisms, Signaling Transduction Elements and Novel Targeting Therapies.- Involvement of Lipid Rafts in Growth Factor Receptors-Mediated Signaling for Cancer Metastasis.- Cadherin-Catenin Signaling in Ovarian Cancer Progression.- PTP4A3, a Signal Molecule Deregulated in Uveal Melanoma Metastasis.- Signal Transduction Pathways Involved in Hepatocarcinogenesis and Metastasis of Hepatoma.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 300 pp. Englisch. N� de r�f. du vendeur 9789400733589

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