Modelling of GPCRs: A Practical Handbook - Couverture rigide

Strasser, Andrea; Wittmann, Hans-Joachim

Couverture rigide

ISBN 10 : 9400745958 ISBN 13 : 9789400745957

Editeur : Springer, 2012

Synopsis

G protein coupled receptors (GPCRs) comprise an important protein family, which is involved in signal transduction in the cell. Besides that a large number of drugs, available on market, address GPCRs. For an efficient and improved development of appropriate drugs, molecular modelling of GPCRs is - in order to understand the ligand-receptor interactions and functionality of GPCRs on molecular level - an important tool. The book "Modelling of GPCRs - a practical handbook" is focussed onto a practical introduction into molecular modelling of GPCRs. This book is very useful for beginners in GPCR modelling, but also addresses the advanced GPCR modeller: On the one hand, the book introduces principles of GPCR modelling, including extensive examples. On the other hand, detailed outlooks onto advanced GPCR modelling techniques are presented. Furthermore, the book includes important data, like information about crystal structures in a summarized manner or amino acid sequences, which are essential for GPCR modelling in general. Due to an increase in efficacy and data handling most modellers use LINUX as operating system. To address this, a summary of most important LINUX commands with examples is presented within the book.

Détails de l'édition

• Éditeur: Springer
• Date d'édition: 2012
• Langue: anglais
• ISBN 10: 9400745958
• ISBN 13: 9789400745957
• Reliure: Relié
• Nombre de pages: 228
• Coordonnées du fabricant: non disponible
• Personne responsable: CMN Printpool Inh. Mathis Neumann; https://www.also.com/ec/cms5/en_6000/6000/index.jsp; ; Friedrich-Karl-Str. 9; Hamburg; Allemagne