Transcriptional and Translational Regulation of Stem Cells - Couverture rigide

Livre 143 sur 544: Advances in Experimental Medicine and Biology
 
9789400766204: Transcriptional and Translational Regulation of Stem Cells

Synopsis

This volume describes the latest findings on transcriptional and translational regulation of stem cells. Both transcriptional activators and repressors have been shown to be crucial for the maintenance of the stem cell state. A key element of stem cell maintenance is repression of differentiation factors or developmental genes - achieved transcriptionally, epigenetically by the Polycomb complex, and post-transcriptionally by RNA-binding proteins and microRNAs. This volume takes two approaches to this topic - (1) illustrating the general principles outlined above through a series of different stem cell examples - embryonic, iPS and adult stem cells, and (2) describing several molecular families that have been shown to have roles in regulation of multiple stem cell populations.

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Autres éditions populaires du même titre

9789402401820: Transcriptional and Translational Regulation of Stem Cells

Edition présentée

ISBN 10 :  9402401822 ISBN 13 :  9789402401820
Editeur : Springer, 2016
Couverture souple