DNA Repair of Cancer Stem Cells - Couverture souple

Couverture souple

ISBN 10 : 9400797052 ISBN 13 : 9789400797055

Editeur : Springer, 2014

Synopsis

The existence of ‘cancer stem cells’ (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuous characterization in a variety of solid tumors has lead to an abundance of evidence supporting their existence. CSCs are believed to be responsible for resistance against conventional treatment regimes of chemotherapy and radiation, ultimately, leading to metastasis and patient demise. To help aid clinicians, pharmaceutical companies and academic labs investigating how to better kill these highly aggressive cells we have summarized the DNA repair mechanism(s) and their role in the maintenance and regulation of both normal and cancer stem cells. Our book represents a comprehensive investigation into the highly effective DNA repair mechanisms of CSCs and what we need to understand in order to develop more advanced therapies to eradicate them from patients. Currently, there are no other published works entirely on DNA repair and Cancer Stem Cells. In addition, our book provides a comprehensive overview of CSC isolation and characterization from a variety of solid tumor types.

A propos du livre

Présentation de l'éditeur

Therapies targeting cancer stem cells are set for a bright medical future. The first volume to focus on the DNA repair mechanisms of both normal and cancer stem cells, this guide is a vital aid to clinicians, pharmaceutical companies and academics alike.

Détails de l'édition

• Éditeur: Springer
• Date d'édition: 2014
• Langue: anglais
• ISBN 10: 9400797052
• ISBN 13: 9789400797055
• Reliure: Broché
• Nombre de pages: 188
• Éditeur: Mathews Lesley A, Cabarcas Stephanie M, Hurt Elain
• Coordonnées du fabricant: non disponible
• Personne responsable: CMN Printpool Inh. Mathis Neumann; https://www.also.com/ec/cms5/en_6000/6000/index.jsp; ; Friedrich-Karl-Str. 9; Hamburg; Allemagne