Synopsis
Introduction. Scope of the Work. Guidelines for Research with Animals. Moral and Ethical Considerations. Principles and Training Programs. Design of Candidate Radiopharmaceuticals. Identification of Clinical Need. Choice of Radionuclide. Screening Studies. Drug Development. Concept of Biological Models. In vitro Models. Choice of Biological Models. Species Variations. Transgenic Mice. Dogs and Kangaroos. Poison Arrow Frog. Giraffe. Tomographic Physiological Chemistry. ARG. SPET. PET. SIMS. Keyword Guide to Selection of Biological Models. References. Glossary of Abbreviations.
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