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Molecular Basis of Specificity in Nucleic Acid-drug Interactions: Proceedings of the Twenty-third Jerusalem Symposium on Quantum Chemistry and Biochemistry Held in Jerusalem, Israel, May 14 17, 1990 - Couverture souple
Synopsis
One of the central problems in the study of the mechanism of DNA-ligand interactions is the existence and nature of sequence specificity with respect to the base pairs of DNA. The presence of such a specificity could be of particular significance because it might possibly mean the involvement of specific genes in the effectiveness of the different drugs. The elucidation of the factors responsible for the specificity could then be important for the development of compounds susceptible to contribute to the control of gene expression and also to the development of rationally conceived, improved new generations of effective and specific chemotherapeutic agents. Important recent achievements, experimental and theoretical, in the analysis of such sequence specificities open prospects for possible rapid progress in this field. The 23rd Jerusalem symposium was devoted to the exploration of these recent achievements in relation to many types of ligand, with special emphasis on antitumor drugs. All major types of interaction, intercalation, groove binding, covalent linking, coordination, have been considered. So was also the effect of the interaction on the structure and properties of the nucleic acids and the relationship between the interaction and biological or pharmacological activities. We feel that this Volume presents a relatively complete up-to-date account of the state of the art in this important field of research.
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Molecular Basis of Specificity in Nucleic Acid-Drug Interactions (eng)
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Molecular Basis of Specificity in Nucleic Acid-Dru
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Molecular Basis of Specificity in Nucleic Acid-Drug Interactions: Proceedings of the Twenty-Third Jerusalem Symposium on Quantum Chemistry and Biochemistry Held in Jerusalem, Israel, May 14-17, 1990
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Molecular Basis of Specificity in Nucleic Acid-Drug Interactions
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Springer Netherlands, Springer Netherlands Okt 2012, 2012
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ISBN 13 : 9789401056571
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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -One of the central problems in the study of the mechanism of DNA-ligand interactions is the existence and nature of sequence specificity with respect to the base pairs of DNA. The presence of such a specificity could be of particular significance because it might possibly mean the involvement of specific genes in the effectiveness of the different drugs. The elucidation of the factors responsible for the specificity could then be important for the development of compounds susceptible to contribute to the control of gene expression and also to the development of rationally conceived, improved new generations of effective and specific chemotherapeutic agents. Important recent achievements, experimental and theoretical, in the analysis of such sequence specificities open prospects for possible rapid progress in this field. The 23rd Jerusalem symposium was devoted to the exploration of these recent achievements in relation to many types of ligand, with special emphasis on antitumor drugs. All major types of interaction, intercalation, groove binding, covalent linking, coordination, have been considered. So was also the effect of the interaction on the structure and properties of the nucleic acids and the relationship between the interaction and biological or pharmacological activities. We feel that this Volume presents a relatively complete up-to-date account of the state of the art in this important field of research. 616 pp. Englisch. N° de réf. du vendeur 9789401056571
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Molecular Basis of Specificity in Nucleic Acid-Drug Interactions
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Springer Netherlands, 2012
ISBN 10 : 9401056579
ISBN 13 : 9789401056571
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Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Proceedings of the Twenty-Third Jerusalem Symposium on Quantum Chemistry and Biochemistry, held in Jerusalem, Israel, May 14-17, 1990 One of the central problems in the study of the mechanism of DNA-ligand interactions is the existence and nature of s. N° de réf. du vendeur 5832317
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Molecular Basis of Specificity in Nucleic Acid-drug Interactions: Proceedings of the Twenty-third Jerusalem Symposium on Quantum Chemistry and Biochemistry Held in Jerusalem, Israel, May 1417, 1990
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Molecular Basis of Specificity in Nucleic Acid-Drug Interactions
Edité par
Springer Netherlands, Springer Netherlands Okt 2012, 2012
ISBN 10 : 9401056579
ISBN 13 : 9789401056571
Neuf
Taschenbuch
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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -One of the central problems in the study of the mechanism of DNA-ligand interactions is the existence and nature of sequence specificity with respect to the base pairs of DNA. The presence of such a specificity could be of particular significance because it might possibly mean the involvement of specific genes in the effectiveness of the different drugs. The elucidation of the factors responsible for the specificity could then be important for the development of compounds susceptible to contribute to the control of gene expression and also to the development of rationally conceived, improved new generations of effective and specific chemotherapeutic agents. Important recent achievements, experimental and theoretical, in the analysis of such sequence specificities open prospects for possible rapid progress in this field. The 23rd Jerusalem symposium was devoted to the exploration of these recent achievements in relation to many types of ligand, with special emphasis on antitumor drugs. All major types of interaction, intercalation, groove binding, covalent linking, coordination, have been considered. So was also the effect of the interaction on the structure and properties of the nucleic acids and the relationship between the interaction and biological or pharmacological activities. We feel that this Volume presents a relatively complete up-to-date account of the state of the art in this important field of research.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 616 pp. Englisch. N° de réf. du vendeur 9789401056571
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Molecular Basis of Specificity in Nucleic Acid-Drug Interactions | Proceedings of the Twenty-Third Jerusalem Symposium on Quantum Chemistry and Biochemistry Held in Jerusalem, Israel, May 14-17, 1990
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Taschenbuch. Etat : Neu. Molecular Basis of Specificity in Nucleic Acid-Drug Interactions | Proceedings of the Twenty-Third Jerusalem Symposium on Quantum Chemistry and Biochemistry Held in Jerusalem, Israel, May 14-17, 1990 | A. Pullman (u. a.) | Taschenbuch | Jerusalem Symposia | x | Englisch | 2012 | Springer | EAN 9789401056571 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on Demand. N° de réf. du vendeur 105703644
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Molecular Basis of Specificity in Nucleic Acid-Drug Interactions : Proceedings of the Twenty-Third Jerusalem Symposium on Quantum Chemistry and Biochemistry Held in Jerusalem, Israel, May 14¿17, 1990
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Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - One of the central problems in the study of the mechanism of DNA-ligand interactions is the existence and nature of sequence specificity with respect to the base pairs of DNA. The presence of such a specificity could be of particular significance because it might possibly mean the involvement of specific genes in the effectiveness of the different drugs. The elucidation of the factors responsible for the specificity could then be important for the development of compounds susceptible to contribute to the control of gene expression and also to the development of rationally conceived, improved new generations of effective and specific chemotherapeutic agents. Important recent achievements, experimental and theoretical, in the analysis of such sequence specificities open prospects for possible rapid progress in this field. The 23rd Jerusalem symposium was devoted to the exploration of these recent achievements in relation to many types of ligand, with special emphasis on antitumor drugs. All major types of interaction, intercalation, groove binding, covalent linking, coordination, have been considered. So was also the effect of the interaction on the structure and properties of the nucleic acids and the relationship between the interaction and biological or pharmacological activities. We feel that this Volume presents a relatively complete up-to-date account of the state of the art in this important field of research. N° de réf. du vendeur 9789401056571
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