Articles liés à I Domain in Integrins
Synopsis
The integrin family is composed of 24 members and approximately ten years ago (2003) we published a book devoted to the nine I domain integrin subunits. In this second edition, I am pleased that most of the original authors have been able to contribute to the updated version.
I domain containing integrins include collagen receptors and leukocyte receptors. In 2003 the knockout mouse phenotypes for all of the I domain integrins had not yet been published; they are now, and are summarized and discussed in this edition.
Interestingly, a recent 10 integrin mutation in dogs has indicated that collagen-binding integrins in the musculoskeletal system might have much more severe phenotypes in larger animals/humans compared to the mild integrin phenotypes observed in collagen-binding integrin deficient mice. This finding is further discussed in the book.
In the cancer field, the microenvironment is taking center stage, and here collagen receptors on fibroblasts are predicted to play important roles in paracrine signaling, in regulating tissue stiffness and matrix remodeling.
New technologies, new mouse models in combination with analyses of I integrins in larger animals/humans are thus predicted to increase our knowledge about this group of receptors. With this in mind we look forward to another 10 years of research with I domain integrins.
Les informations fournies dans la section « Synopsis » peuvent faire référence à une autre édition de ce titre.
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I domain integrins.
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Dordrecht, Springer., 2014
ISBN 10 : 940179152X
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XIV, 179 p. Hardcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Stamped. Advances in experimental medicine and biology; 819. Sprache: Englisch. N° de réf. du vendeur 8901DB
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I Domain Integrins (Advances in Experimental Medicine and Biology, 819)
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I Domain Integrins (Advances in Experimental Medicine and Biology, 819)
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I Domain Integrins (Advances in Experimental Medicine and Biology, 819)
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I Domain Integrins
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Springer Netherlands Jul 2014, 2014
ISBN 10 : 940179152X
ISBN 13 : 9789401791526
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Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The integrin family is composed of 24 members and approximately ten years ago (2003) we published a book devoted to the nine I domain integrin subunits. In this second edition, I am pleased that most of the original authors have been able to contribute to the updated version.I domain containing integrins include collagen receptors and leukocyte receptors. In 2003 the knockout mouse phenotypes for all of the I domain integrins had not yet been published; they are now, and are summarized and discussed in this edition.Interestingly, a recent 10 integrin mutation in dogs has indicated that collagen-binding integrins in the musculoskeletal system might have much more severe phenotypes in larger animals/humans compared to the mild integrin phenotypes observed in collagen-binding integrin deficient mice. This finding is further discussed in the book.In the cancer field, the microenvironment is taking center stage, and here collagen receptors on fibroblasts are predicted to play important roles in paracrine signaling, in regulating tissue stiffness and matrix remodeling.New technologies, new mouse models in combination with analyses of I integrins in larger animals/humans are thus predicted to increase our knowledge about this group of receptors. With this in mind we look forward to another 10 years of research with I domain integrins. 196 pp. Englisch. N° de réf. du vendeur 9789401791526
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I Domain Integrins
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Springer Netherlands, 2014
ISBN 10 : 940179152X
ISBN 13 : 9789401791526
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Gebunden. Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Features the latest information on I Domain IntegrinsFeatures the latest information on these transmembrane receptorsWill be a valuable source of information for academic, as well as biotech and pharma researchersThe integrin fam. N° de réf. du vendeur 5838087
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I Domain Integrins
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Etat : New. pp. 196. N° de réf. du vendeur 26142324128
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I Domain Integrins
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Etat : New. Print on Demand pp. 196 50 Illus. (32 Col.). N° de réf. du vendeur 135007871
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I Domain Integrins
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I Domain Integrins
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Springer Netherlands, Springer Netherlands Jul 2014, 2014
ISBN 10 : 940179152X
ISBN 13 : 9789401791526
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Buch. Etat : Neu. Neuware -The integrin family is composed of 24 members and approximately ten years ago (2003) we published a book devoted to the nine I domain integrin subunits. In this second edition, I am pleased that most of the original authors have been able to contribute to the updated version.I domain containing integrins include collagen receptors and leukocyte receptors. In 2003 the knockout mouse phenotypes for all of the I domain integrins had not yet been published; they are now, and are summarized and discussed in this edition.Interestingly, a recent 10 integrin mutation in dogs has indicated that collagen-binding integrins in the musculoskeletal system might have much more severe phenotypes in larger animals/humans compared to the mild integrin phenotypes observed in collagen-binding integrin deficient mice. This finding is further discussed in the book.In the cancer field, the microenvironment is taking center stage, and here collagen receptors on fibroblasts are predicted to play important roles in paracrine signaling, in regulating tissue stiffness and matrix remodeling.New technologies, new mouse models in combination with analyses of I integrins in larger animals/humans are thus predicted to increase our knowledge about this group of receptors. With this in mind we look forward to another 10 years of research with I domain integrins.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 196 pp. Englisch. N° de réf. du vendeur 9789401791526
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