Regulation of Cytokine Gene Expression in Immunity and Diseases - Couverture rigide

Livre 262 sur 544: Advances in Experimental Medicine and Biology
 
9789402409192: Regulation of Cytokine Gene Expression in Immunity and Diseases

Synopsis

This book explores the major cytokines, such as IL-1 and IFN-γ, with respect to the regulation of their gene expression and protein production in specific immune cell types. It discusses both healthy physiological settings and in pathological situations in which the expression of some cytokines could be dysregulated, resulting in either immunodeficiency or exacerbated inflammatory sequelae in animal models as well as in human patients. Cytokines are important regulators of immune responses that require the highly coordinated participation and communication of multiple cell types. The expression of cytokines by various producer cell types is therefore carefully regulated in response to environmental cues at multiple levels: transcription, translation and posttranslational modification. Presentingcutting-edge advances in our understanding of the regulation of cytokine expression, this book is a valuable resource for anyone involved or interested in immune regulation.

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À propos de l?auteur

Dr. Xiaojing Ma is a professor from Department of Microbiology and Immunology, Weill Cornell Medical College, USA. He is also the chair professor and associate dean of School of Life Sciences and Biotechnology, Shanghai Jiao Tong University. He serves as the associate editor of The Journal of Immunology, and is in the editorial board of several international journals, such as The Journal of Experimental Medicine, Annual Review of Biomedical Science and Cellular and Molecular Immunology. His research focuses on molecular regulation of cytokine gene expression and their immunological activities in inflammatory diseases, and he has published more than 80 research articles on top journals in this field.

Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.

Autres éditions populaires du même titre

9789402414363: Regulation of Cytokine Gene Expression in Immunity and Diseases

Edition présentée

ISBN 10 :  9402414363 ISBN 13 :  9789402414363
Editeur : Springer, 2018
Couverture souple