Foreword.- Historical perspectives on management of acute myocardial infarction.- Pre-hospital diagnosis and management of acute myocardial infarction.- STEMI network and logistics - rural vs. urban.- Cath lab design, staffing, training.- Patient preparation and vascular access for primary PCI.- Management of intra-coronary thrombus.- Culprit only artery versus multi-vessel disease.- Pharmacologic therapies in primary PCI - antiplatelet agents.- Pharmacologic therapies in primary PCI - glycoproteins, heparins, bivalirudins, etc.- Pharmacologic therapies in primary PCI - inotropes, etc.- Drug-eluting stents vs. bare-metal stents in Primary PCI - Is there still a debate?.- Drug-eluting balloons in primary PCI.- High bleeding risk scenarios in primary PCI.- Mechanical complications of myocardial infarction - free-wall rupture, VSD, acute MR.- The role of mechanical circulatory support in primary PCI - IABP, ECMO, IMPELLA, LUCAS?.- Methods of reducing infarct size and reperfusion injury in primary PCI.- Time to reperfusion, door to balloon times, and how to reduce them.- Utilization of facilitated and rescue angioplasty in primary PCI.- Primary angioplasty: the economics.- Role of bypass surgery in acute myocardial infarction: indications, timing, outcome.- Role of intravascular imaging in emergency PCI.- Patients ineligible for primary PCI .
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