Triple-Negative Breast Cancer - Couverture rigide

Couverture rigide

ISBN 10 : 9813277750 ISBN 13 : 9789813277755

Editeur : World Scientific Publishing Co Pte Ltd, 2020

Synopsis

Triple-negative breast cancer (TNBC) represents a challenge clinically due to the lack of actionable targets coupled with an aggressive disease course and a worse prognosis compared to patients with other breast cancer subtypes. This book covers aspects of TNBC ranging from epidemiology, biology, molecular classification, to currently available and potentially new therapeutics options for TNBC. This book includes a range of recommended resources, including recent reviews, schematic illustrations, and information for patients with TNBC

A propos du livre

À propos de l?auteur

Xiyun Deng is a professor of pathophysiology and molecular pathology and chair of Department of Basic Medical Sciences at Hunan Normal University School of Medicine located in Changsha, Hunan, China. He is the founder and currently serves as director of Key Laboratory of Translational Cancer Stem Cell Research at Hunan Normal University. Funded by the Natural Science Foundation of China (NSFC) and other funding agencies for over 15 years, his research interests cover the molecular mechanisms of cancer metastasis and, more recently, the experimental therapeutics targeting cancer stem cells. The major contributions he and his team have made over many years of research include: 1) the discovery that post-translational modifications of non-histone proteins play crucial roles in metastasis and drug-induced cellular stress responses in cancer stem cells; and 2) the development and mechanistic studies of cancer stem cell–targeting drugs against cancer with a particular focus on triple-negative breast cancer. He has published over 100 papers including first-author and/or corresponding-author articles/reviews in Blood, Clinical Cancer Research, Cancer Treatment Reviews, ACS Applied Materials & Interfaces, International Journal of Cancer, European Journal of Cancer, etc. As a research-oriented scholar, he is enthusiastically engaged in teaching activities. The undergraduates and graduates he mentored got several national-level awards including the ""Challenge Cup"" (2nd Prize), which is one of China's highest honors for undergraduates.

Faqing Tang is a professor of clinical pathology and laboratory medicine at Central South University, China. He serves as director of Clinical Laboratory and Medical Research Center, Hunan Cancer Hospital & the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University. He is director of Key Laboratory of Cancer Target Genes of Hunan Province, China. The research of the Tang laboratory focuses on the molecular carcinogenesis of cancer and the experimental therapeutics targeting oncogene. The major contributions he and his team have made include: 1) development and evaluation of new clinical laboratory technology, diagnostic reagents, and quality control software and approaches; 2) development of novel biomarkers for diagnosis/monitoring and therapeutic intervention of cancer including circulating tumor cells. He has published over 100 papers including first-author and/or corresponding-author articles in Cancer Research, Journal of Biological Chemistry, PLoS One, BMC Cancer, etc.

Détails de l'édition

• Éditeur: World Scientific Publishing Co Pte Ltd
• Date d'édition: 2020
• Langue: anglais
• ISBN 10: 9813277750
• ISBN 13: 9789813277755
• Reliure: Relié
• Nombre de pages: 248
• Éditeur: Deng Xiyun, Tang Faqing, Rosol Thomas J
• Coordonnées du fabricant: non disponible
• Personne responsable: gpsr@libri.de; gpsr@libri.de; ; Friedensallee 273; Hamburg; 22763; Allemagne