Soft Tissue Tumors Diagnostic Pathology Textbook: Evidence-Based Approaches to Morphologic Patterns, Immunoprofiles, and Molecular Testing for Anatomic Trainees - Couverture souple

Henson, MD Ramon C.

Couverture souple

ISBN 13 : 9798952839618

Editeur : Ramon C. Henson, 2026

Synopsis

Move From the Pattern on the Slide to the Fusion That Settles the Diagnosis

Sixteen chapters cover the full range of mesenchymal neoplasia, from adipocytic, fibroblastic, smooth muscle, skeletal muscle, vascular, and nerve sheath tumors to synovial sarcoma, small round cell sarcomas, and pleomorphic sarcomas. Built on the fifth edition of the WHO classification with later refinements, the book teaches how a lineage of differentiation produces an architecture, how immunostains narrow the field, and how a defining gene fusion or mutation confirms the diagnosis. It is written for anatomic pathology residents, bone and soft tissue fellows, and surgical pathologists who see sarcoma only occasionally.

Every chapter gives you three five-part pattern entries and a chapter-end pattern index, so a difficult case at the microscope leads to a specific stain, a specific test, and a specific trap to avoid.

What You Will Be Able to Do

Biopsy strategy, frozen section, grossing, inking, and tissue triage - protect the specimen and margins before any slide is cut

Immunohistochemistry, FISH, RT-PCR, and sequencing principles - choose the informative test and interpret surrogate markers correctly

Liposarcoma subtypes with MDM2 amplification and DDIT3 rearrangement - separate well-differentiated, dedifferentiated, and myxoid tumors from lipomatous mimics

Fibroblastic, smooth muscle, and vascular tumors - recognize desmoid-type fibromatosis, solitary fibrous tumor, leiomyosarcoma, and angiosarcoma patterns

Gastrointestinal stromal tumor biology, KIT and PDGFRA signaling, and SDH deficiency - apply risk stratification and understand targeted therapy resistance

Synovial sarcoma, epithelioid sarcoma, and clear cell sarcoma - resolve fusion-driven spindle cell tumors with the right ancillary study

Ewing sarcoma, CIC-rearranged and BCOR-altered sarcomas, and desmoplastic small round cell tumor - work through the small round cell diagnostic algorithm

Grading, AJCC staging, synoptic reporting, and post-neoadjuvant assessment - write reports the tumor board can act on

Add this textbook to your sign-out room and diagnose soft tissue tumors with a method that holds up as the classification changes.

Détails de l'édition

• Éditeur: Ramon C. Henson
• Date d'édition: 2026
• Langue: anglais
• ISBN 13: 9798952839618
• Reliure: Tapa blanda
• Nombre de pages: 374
• Coordonnées du fabricant: non disponible
• Personne responsable: gpsr@libri.de; gpsr@libri.de; ; Europaallee 1; Bad Hersfeld; 36244; Allemagne