Aging and Age-Related Disorders

. Ed(s): Bondy, Stephen C.; Maiese, Kenneth

ISBN 10: 1607616017 / ISBN 13: 9781607616016

Edité par Humana Press Inc., 2010

This book examines the interactive relationship between systems in the body, such as the nervous system and vascular system, that can enhance or sometimes limit cellular longevity. It details medical applications that should lead to improved health care. Editor(s): Bondy, Stephen C.; Maiese, Kenneth. Series: Oxidative Stress in Applied Basic Research and Clinical Practice. Num Pages: 472 pages, 7 black & white tables, biography. BIC Classification: MFGC; MJX; PSF. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly. Dimension: 239 x 165 x 37. Weight in Grams: 954. . 2010. Hardback. . . . . Books ship from the US and Ireland. N° de réf. du vendeur V9781607616016

Synopsis :

This book examines the interactive relationship between systems in the body, such as the nervous system and vascular system, that can enhance or sometimes limit cellular longevity. It details medical applications that should lead to improved health care.

Présentation de l'éditeur: Features that characterize the aging process include the gradual accumulation of cell damage after prolonged exposure to oxidative and inflammatory events over a lifetime. In addition to the accretion of lesions, the intrinsic levels of pro-oxidant and aberrant immune responses are elevated with age. These adverse events are often further enhanced by the chronic and slow progressing diseases that characterize the senescent brain and cardiovascular system. The incidence of some disorders such as Alzheimer's disease and vascular diseases are sufficiently prevalent in the extreme elderly that these disorders can arguably be considered "normal". Aging and Aging-Related Disorders examines the interface between normal and pathological aging, and illustrates how this border can sometimes be diffuse. It explores and illustrates the processes underlying the means by which aging becomes increasingly associated with inappropriate levels of free radical activity and how this can serve as a platform for the progression of age-related diseases. The book provides chapters that examine the interactive relationship between systems in the body that can enhance or sometimes even limit cellular longevity. In addition, specific redox mechanisms in cells are discussed. Another important aspect for aging discussed here is the close relationship between the systems of the body and exposure to environmental influences of oxidative stress that can affect both cellular senescence and a cell's nuclear DNA. What may be even more interesting to note is that these external stressors are not simply confined to illnesses usually associated with aging, but can be evident in maturing and young individuals. A broad range of internationally recognized experts have contributed to this book. Their aim is to successfully highlight emerging knowledge and therapy for the understanding of the basis and development of aging-related disorders.

Détails bibliographiques

Titre : Aging and Age-Related Disorders
Éditeur : Humana Press Inc.
Date d'édition : 2010
Reliure : Couverture rigide
Etat : New