Alternating Electric Fields Therapy in Oncology : A Practical Guide to Clinical Applications of Tumor Treating Fields

Eric T. Wong

ISBN 10: 3319305743 / ISBN 13: 9783319305745

Edité par Springer, Berlin, Springer, 2016

A propos de cet article

Druck auf Anfrage Neuware - Printed after ordering - This concise text provides acomplete overview of alternating electric fields therapy -- also known as tumortreating fields -- for glioblastoma and other types of solid tumormalignancies. Readers are given a fundamental understanding of this novelanti-cancer treatment modality by learning from clinical trial data as well asthe physical and cell biology effects on tumor cells when alternating electricfields are applied both in vitro and in vivo.Chapters illustrate the physicsbehind electric field propagation in space and other media. This isfollowed by a review of our current understanding of the electric field effectson dividing cells - including the disruption of cytokinesis, proper chromosomesegregation and activation on the cell surface chaperons that induceimmunogenic cell death. Data from phase III trials for the treatment ofrecurrent and newly diagnosed glioblastomas are included, as well as some ofthe ancillary post hoc analyses thatwere performed by variousinvestigators. The remainder of the chapter covers other solid tumormalignancies, including non-small cell lung cancer, pancreatic cancer andovarian cancer, as this treatment modality is being applied to systemicmalignancies.Alternating Electric FieldsTherapy in Oncology offers oncologists,neurologists, radiation oncologists, biomedical engineers, cell biologists andmitosis researchers the fundamentals needed for clinical practice.

N° de réf. du vendeur 9783319305745

Détails bibliographiques

• Titre: Alternating Electric Fields Therapy in Oncology : A Practical Guide to Clinical Applications of Tumor Treating Fields
• Éditeur: Springer, Berlin, Springer
• Date de parution: 2016
• Langue: anglais
• ISBN à 10 chiffres: 3319305743
• ISBN à 13 chiffres: 9783319305745
• Reliure: Buch
• État de l'article: Neu
• Dimensions: 249 L x 176 H x 15 P (en millimètres) 249 millimètres de largeur par 176 millimètres de hauteur par 15 millimètres de profondeur
• Poids: 332 grammes

A propos de ce titre

Synopsis

This concise text provides a complete overview of alternating electric fields therapy -- also known as tumor treating fields -- for glioblastoma and other types of solid tumor malignancies. Readers are given a fundamental understanding of this novel anti-cancer treatment modality by learning from clinical trial data as well as the physical and cell biology effects on tumor cells when alternating electric fields are applied both in vitro and in vivo.

Chapters illustrate the physics behind electric field propagation in space and other media. This is followed by a review of our current understanding of the electric field effects on dividing cells - including the disruption of cytokinesis, proper chromosome segregation and activation on the cell surface chaperons that induce immunogenic cell death. Data from phase III trials for the treatment of recurrent and newly diagnosed glioblastomas are included, as well as some of the ancillary post hoc analyses thatwere performed by various investigators. The remainder of the chapter covers other solid tumor malignancies, including non-small cell lung cancer, pancreatic cancer and ovarian cancer, as this treatment modality is being applied to systemic malignancies.

Alternating Electric Fields Therapy in Oncology offers oncologists, neurologists, radiation oncologists, biomedical engineers, cell biologists and mitosis researchers the fundamentals needed for clinical practice.

À propos de l?auteur

Eric T. Wong, MD

Associate Professor of Neurology

Beth Israel Deaconess Medical Center

330 Brookline Avenue

Boston, MA 02215, USA