Amyloid Protein Precursor in Development, Aging and Alzheimer's Disease (Research and Perspectives in Alzheimer's Disease) -

Colin L. Masters

ISBN 10: 3540577882 / ISBN 13: 9783540577881

Edité par Springer, 1994

A propos de cet article

N° de réf. du vendeur C32.j

Détails bibliographiques

• Titre: Amyloid Protein Precursor in Development, Aging and Alzheimer's Disease (Research and Perspectives in Alzheimer's Disease) -
• Éditeur: Springer
• Date de parution: 1994
• Langue: anglais
• ISBN à 10 chiffres: 3540577882
• ISBN à 13 chiffres: 9783540577881
• Reliure: Couverture rigide
• État de l'article: Neuf

A propos de ce titre

Synopsis

This is a summary of the last ten years' research on Alzheimer's disease. Genetic mutations in the gene with codes for amyloid precursor protein (APP) have now been shown to cause Alzheimer's disease in some families. Other genetic loci are now being discovered which relate to Alzheimer's disease in families. Understanding the normal structure and function of the APP gene product will eventually provide avenues for developing specific therapeutic strategies targeted at the amyloid deposition in the brain. Drugs which can inhibit or dissolve the amyloid, affect the synthesis and proteolysis of APP, or which regulate the activity of the APP gene, are explored in the text.