Titre: A Bioinformatics-Driven Investigation of Biomarkers in the Wnt Signaling Pathway for Cancer Signaling
�diteur: Independent Publisher
Date de parution: 2024
Langue: anglais
ISBN � 13 chiffres: 9798227849342
Reliure: Couverture souple
�tat de l'article: As New

A propos de ce titre

Synopsis

Cell signaling is a way of communication among the living cells and involves the processing of biochemical information to regulate metabolic and cellular activities of the organism. The process of signaling initiates with a chemical species (i.e. ligands or signaling molecules) and ends with the cellular responses. The signal molecules are recognized by the receptors on the surface of target cells and the message is transferred inside the cell in series of steps, the signal transduction pathway, to produce the desired effects. Many signaling pathways have been studied for their involvement in cellular processes such as differentiation and proliferation. One such pathway is Wnt-signaling pathway which is an ancient and highly conserved among all metazoans; it is known to have roles in regulating life processes such as embryonic development, cell growth and survival, cell differentiation, migration and polarity (Wodarz et al., 1998). The term Wnt is derived from the name of two genes viz. wingless gene of Drosophila which is a segment polarity gene and its vertebrate homolog integrated or int-1 (Komiya and Habas, 2008). The extracellular signaling molecule of this pathway (i.e. ligand) is a glycoprotein known as Wnt, which binds to, and dimerize, two receptors namely LRP6/5 and Fz. The downstream signal is transported to the nucleus and promotes the transcription of Wnt responsive genes which ultimately regulate a wide variety of cellular processes including cell fate determination, motility, polarity, primary axis formation, stem cell renewal and organogenesis. The intracellular

Les informations fournies dans la section � A propos du livre � peuvent faire r�f�rence � une autre �dition de ce titre.

Description de la librairie

SuperBookDeals.com is your top source for finding new books at the absolute lowest prices, guaranteed ! We offer big discounts - everyday - on millions of titles in virtually any category, from Architecture to Zoology -- and everything in between. Discover great deals and super-savings, on professional books, text book titles, the newest computer guides, or your favorite fiction authors. You'll find it all - at HUGE SAVINGS - at SuperBookDeals. Browse through our complete online product catalog today. Serving customers around the world for years, we help thousands find just the books they're looking for -- at incredibly low, bargain prices.

Visitez la page d�accueil du vendeur

Informations commerciales relatives au vendeur

Expert Trading Limited
9220 Rumsey Road, Suite 101, Columbia, MD, 21045, U.S.A.

Conditions de vente et de livraison

Conditions g�n�rales de vente

Company Name: GreatBookPrices
Legal Entity: Expert Trading, LLC
Address: 6310 Stevens Forest, suite 200, Columbia MD 21046
Email address: CustomerService@SuperBookDeals.com
Phone number: 410-964-0026
consumer complaints can be addressed to address above
Registration #: 52-1713923
Authorized representative: Danielle Hainsey

Conditions d'exp�dition

Our warehouses across the globe are fully operational without substantial delays. We are working hard and continue to overcome the daily challenges presented by COVID-19. We appreciate your understanding.

Internal processing of your order will take about 1-2 business days. Please allow an additional 4-14 business days for Media Mail delivery. We have multiple ship-from locations - MD,IL,NJ,UK,IN,NV,TN & GA