Synopsis
Overview and aims. This book is intended as a self-contained guide to the entire ?eld of bioinformatics, interpreted as the application of information science to - ology. There is strong underlying belief that information is a profound concept underlying biology, and familiarity with the concepts of information should make it possible to gain many important new insights into biology. In other words, the vision underpinning this book goes beyond the narrow interpretation of bioinf- matics sometimes encountered, which may con?ne itself to speci?c tasks such as the attempted identi?cation of genes in a DNA sequence. Organization and features. The chapters are grouped into three parts, cov- ing the relevant fundamentals of information science, overviewing all of biology, and surveying applications. Thus Part I (fundamentals) carefully explains what - formation is, and discusses attributes such as value and quality, and its multiple signi?cations of accuracy, meaning, and effect. The transmission of information through channels is described. Brief summaries of the necessary elements of set theory, combinatorics, probability, likelihood, clustering, and pattern recognition are given. Conceptssuch as randomness,complexity,systems and networks,needed fortheunderstandingofbiologicalorganization,arealso discussed. PartII(biology) covers both organismal (ontogeny and phylogeny,as well as genome structure) and molecular aspects. Part III (applications) is devoted to the most important prac- cal applications of bioinformatics, notably gene identi?cation, transcriptomics, p- teomics, interactomics (dealing with networks of interactions), and metabolomics.
Présentation de l'éditeur
The field of bioinformatics continues to develop energetically. This comprehensive second edition covers new findings using the successful formula of the original text. Bioinformatics: An Introduction is structured into three parts devoted to Information, Biology and Applications. Every section of the book has been thoroughly updated, and expanded where relevant, to take account of significant new discoveries and realizations of the importance of certain concepts. Furthermore new chapters on Algorithms, Data Processing and Biotechnology have been added. Emphasis is placed on the underlying fundamentals and acquisitions of a broad and comprehensive grasp of the field as a whole. This second edition is intended to be a complete study companion for the advanced undergraduate or graduate student. It is self-contained, bringing together the multiple disciplines necessary for a profound grasp of the field into a coherent whole, allowing the reader to gain much insight into the state of art of bioinformatics.
Les informations fournies dans la section « A propos du livre » peuvent faire référence à une autre édition de ce titre.
