Biologically Active Small Molecules: Modern Applications and Therapeutic Perspectives focuses on small molecules as active pharmacological agents, their pharmacotherapeutically active properties, new approaches in drug discovery using small molecules, and biopharmaceutic approaches for low molecular weight ligands.
Molecules of low mass play a pivotal role in pharmacology because they exhibit multifarious pharmacological effects. Small molecules have become universally popular due to their simple chemistry, easy separation techniques, versatile acceptance for computational studies, large number of places for the substitution of active chemical moieties by well-established synthetic routes with less effort, better quality attributes, and ability to demonstrate numerous biological activities.
This book provides a multidisciplinary approach that delivers the most updated knowledge and advances of some newly developed therapeutically active low molecular weight compounds. It includes chapters that present up-to-date and concise content on the classification, structures, chemical syntheses, medicinal chemistry, pharmacology, biochemical pathways, mechanism of actions, side effects, and adverse effects of small molecule drug discovery. The book covers a broad area by highlighting the advances of inter- and multidisciplinary fields of medicine, chemical sciences, and pharmaceuticals. The flowcharts, figures, illustrations, and diagrams provide important information and will be of great interest for readers.
Debarshi Kar Mahapatra, PhD, is currently an assistant professor in the Department of Pharmaceutical Chemistry, Dadasaheb Balpande College of Pharmacy, Rashtrasant Tukadoji Maharaj Nagpur University, Nagpur, India. He taught medicinal chemistry and computational chemistry at both undergraduate (UG) and postgraduate (PG) levels and has mentored a number of students in various research projects. His area of interest includes computer-assisted rational designing, synthesis of low molecular weight ligands against druggable targets, development of drug delivery systems, and optimization of unconventional formulations. He has published several research papers, review articles, imperative case-studies in various reputed international journals and has presented his original contributions at several international platforms, for which he received several awards by a number of scientific and professional bodies. He has been recognized as Top 2% International Scientists in the S7 List published by Stanford University in the year 2020 with sub-field ranking of 1407. He has contributed several edited books, syllabus-based textbooks, lab manuals, book chapters, magazine articles, and guidebooks on pharmaceutical chemistry, natural products, pharmacology, and pharmaceutics. Presently, he is serving as an approved reviewer and an editorial board member for several journals of international repute. He is an active member of a number of professional and international scientific societies such as ISCA, ISID, ISEI, IPS, APTI, HSGPP, ISPOR, IPS, ISAS, SPER, IPES, etc. He is serving the positions of Chief Advisor and Chief Executive Manager for Indian Pharma Educational Society (IPES), India. In addition to it, he is presently serving as Vice President for Expert Pharmacy Association (EPA), India.
Sanjay Kumar Bharti, PhD
, is an assistant professor at the Institute of Pharmaceutical Sciences, Guru Ghasidas Vishwavidyalaya (A Central University), Bilaspur, India. He has working experience in several organizations, such as Win-Medicare Pvt. Ltd, Meerut, India (as a chemist) and the National Institute of Pharmaceutical Education and Research (NIPER), Hajipur (as a lecturer). He has published several research papers, one book, several book chapters, and several review articles in various reputed journals. His research interest includes synthesis of Schiff’s base, heterocyclic compounds, and metallopharmaceuticals for therapeutics. He is an active member of various scientific and pharmaceutical organizations, including the Indian Pharmaceutical Association, Indian Pharmacy Graduates’ Association, Indian Science Congress Association, among others.
