Biomarkers in Breast Cancer : Molecular Diagnostics for Predicting And Monitoring Therapeutic Effect
Gasparini, Giampietro, M.D. (EDT); Hayes, Daniel F., M.D. (EDT)
ISBN 10: 1588292274 ISBN 13: 9781588292278
Edité par Humana, 2005
Neuf(s)
Couverture rigide
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A propos de cet article
Description :
N° de réf. du vendeur 2095899-n
Synopsis :
Expert laboratory and clinical researchers from around the world review how to design and evaluate studies of tumor markers and examine their use in breast cancer patients. The authors cover both the major advances in sophisticated molecular methods and the state-of-the-art in conventional prognostic and predictive indicators. Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators. Highlights include the evaluation of HER2 and EGFR family members, of p53, and of UPA/PAI-1; the detection of rare cells in blood and marrow; and the detection and analysis of soluble, circulating markers.
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Détails bibliographiques
Titre : Biomarkers in Breast Cancer : Molecular ...
Éditeur : Humana
Date d'édition : 2005
Reliure : Couverture rigide
Etat : New