Biomarkers in Breast Cancer : Molecular Diagnostics for Predicting and Minitoring Therapuetic Effect
Gasparini, Giampietro, M.D. (EDT); Hayes, Daniel F., M.D. (EDT)
ISBN 10: 1617374369 ISBN 13: 9781617374364
Edité par Humana, 2010
Neuf(s)
Couverture souple
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A propos de cet article
Description :
N° de réf. du vendeur 19265386-n
Synopsis :
Expert laboratory and clinical researchers from around the world review how to design and evaluate studies of tumor markers and examine their use in breast cancer patients. The authors cover both the major advances in sophisticated molecular methods and the state-of-the-art in conventional prognostic and predictive indicators. Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators. Highlights include the evaluation of HER2 and EGFR family members, of p53, and of UPA/PAI-1; the detection of rare cells in blood and marrow; and the detection and analysis of soluble, circulating markers.
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Détails bibliographiques
Titre : Biomarkers in Breast Cancer : Molecular ...
Éditeur : Humana
Date d'édition : 2010
Reliure : Couverture souple
Etat : New