Cancer Biology (Paperback)

Langue : anglais

Edité par W.F, 2026

8091989830 / 9788091989831

Vendeur : AussieBookSeller, Truganina, VIC, AustralieAussieBookSeller

Vendeur avec une évaluation de 5 étoiles

Vendeur AbeBooks depuis 22 juin 2007

Livre broché

Etat: Neuf

EUR 85,14

EUR 33,02 expédition 
Expédition depuis Australie vers Etats-Unis

Quantité disponible : 1 disponible

Ajouter au panier
Retours gratuits sous 30 jours

A propos de cet article

Paperback. Cancer is not simply uncontrolled cell growth. It is an evolving biological system in which genetic and epigenetic alterations reshape cellular behavior, disrupt tissue organization, alter interactions with the tumor microenvironment, and create populations capable of invasion, metastasis, persistence, and resistance to treatment.Cancer Biology presents cancer through this mechanistic framework, connecting molecular alterations to cellular behavior, tumor evolution, clinical phenotype, and therapeutic response.The book begins with the biological systems that normally regulate cellular growth, survival, differentiation, genomic integrity, and tissue organization. It then examines how these controls become disrupted through cancer genetics, oncogenes, tumor suppressor genes, DNA damage and repair defects, genomic instability, and epigenetic reprogramming.Particular attention is given to the evolutionary nature of cancer. Tumors are composed of genetically and phenotypically diverse populations that compete, adapt, and respond differently to changing conditions. Clonal evolution, tumor heterogeneity, cellular plasticity, cancer metabolism, replicative immortality, and treatment-driven selection are therefore considered as interconnected processes rather than isolated concepts.The biology of the tumor extends beyond the malignant cell. The tumor microenvironment, including cancer-associated fibroblasts, extracellular matrix, blood vessels, immune cells, inflammatory signals, oxygen availability, and metabolic conditions, can influence tumor growth, invasion, metastasis, immune evasion, and therapeutic response.The book also connects fundamental cancer biology with clinical practice, covering: Cancer genetics, genomics, mutations, copy-number alterations, gene fusions, and driver alterationsOncogenes and tumor suppressors, including TP53, RB, RAS-RAF-MEK-ERK, PI3K-AKT-mTOR, and WNT/b-cateninDNA damage, DNA repair, replication stress, and genomic instabilityEpigenetic regulation, chromatin remodeling, cellular identity, and plasticityClonal evolution, tumor heterogeneity, cancer-cell states, and tumor persistenceCancer metabolism, hypoxia, angiogenesis, inflammation, and the tumor microenvironmentImmune surveillance, immune evasion, immunoediting, and tumor immunologyInvasion, metastasis, organ colonization, dormancy, residual disease, and recurrencePathology, molecular classification, biomarkers, liquid biopsy, staging, and early detectionCancer treatment, including surgery, radiation, cytotoxic, targeted, endocrine, and immune-based therapiesPrecision oncology, single-cell and spatial biology, functional genomics, artificial intelligence, and patient-derived modelsThe emphasis throughout is not merely on what changes in cancer, but on what those changes allow the cancer cell or tumor to do. Cancer is an evolving disease of altered biological regulation. This book connects molecular mechanisms, cellular behavior, genomic evolution, tumor heterogeneity, the tumor microenvironment, clinical disease, and therapeutic response. This item is printed on demand. Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability.…

N° de réf. du vendeur 9788091989831

Détails bibliographiques

Titre
Cancer Biology (Paperback)
Auteur
Wiegand Falkner
Éditeur
W.F
Année de publication
2026
État de l'article
new
Reliure
Paperback
Langue
anglais
ISBN à 10 chiffres
8091989830
ISBN à 13 chiffres
9788091989831

AussieBookSeller

Truganina, VIC, Australie

Vendeur avec une évaluation de 5 étoiles

Vendeur AbeBooks depuis 22 juin 2007

Frais d'expédition de Australie vers Etats-Unis

Article25 à 45 jours ouvrés8 à 14 jours ouvrés
Premier articleEUR 33,02EUR 39,26
Les délais de livraison sont fixés par les vendeurs et varient en fonction du transporteur et du lieu. Les commandes transitant par les douanes peuvent être retardées et les acheteurs sont responsables de tous les droits ou frais associés. Les vendeurs peuvent vous contacter au sujet de frais supplémentaires afin de couvrir toute augmentation des coûts d'expédition de vos articles.

Modes de paiement

  • Visa
  • Mastercard
  • American Express
  • Carte Bleue
  • Apple Pay
  • Google Pay

Profil professionnel du vendeur

The Nile Group Pty Ltd

42 Apex Drive
Truganina, VIC Australie 3029