Cellular and Molecular Immunology (Paperback)

Langue : anglais

Edité par W.F, 2026

2528544499 / 9782528544495

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Paperback. Immunology is not a catalog of cells, cytokines, receptors, and pathways. It is the study of how biological information is recognized, interpreted, and converted into action.Cellular and Molecular Immunology examines the immune system at precisely that level: how molecular signals become cellular decisions, how those decisions lead to tissue responses, and how their failure or redirection result in disease.The book is built around a mechanistic question that remains central across immunology: what information does an immune cell receive, how is that information integrated, and why does the cell respond in one way rather than another?That question provides a consistent framework for understanding innate immune sensing, antigen recognition, signal transduction, lymphocyte development, immune tolerance, inflammation, cellular differentiation, antibody responses, immunological memory, tissue immunity, and immune-mediated pathology.Molecular mechanisms are examined where they determine biological behavior. TCR and BCR signaling, JAK-STAT, NF-kB, MAPK, PI3K-AKT-mTOR, complement, interferon signaling, inflammasomes, antigen processing, MHC biology, V(D)J recombination, costimulation, inhibitory signaling, and metabolic regulation are treated as functional mechanisms rather than disconnected pathways to memorize.The same logic is carried into disease.Autoimmunity is examined as a failure of tolerance and regulatory control. Immunodeficiency is approached through the specific immune function that has been lost and the phenotype that follows. Infection is analyzed according to the pathogen's location, replication strategy, immune evasion mechanisms, and the balance between microbial control and tissue injury. Cancer is considered within the reciprocal relationship between tumor evolution and immune selection. Transplantation is framed through allorecognition, rejection, tolerance, and the consequences of donor-recipient immune conflict.The final part connects these mechanisms to immune-based medicine: monoclonal and bispecific antibodies, cytokine-targeted therapy, checkpoint blockade, cellular immunotherapies, vaccines, immune biomarkers, immune-repertoire analysis, single-cell technologies, and precision immunology.The objective is not to make immunology simpler by removing its complexity. It is to make that complexity structurally intelligible. A rigorous guide to cellular and molecular immunology, connecting immune recognition, signaling, cellular decision-making, tissue responses, immunopathology, and modern immune-based medicine. This item is printed on demand. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.…

N° de réf. du vendeur 9782528544495

Détails bibliographiques

Titre
Cellular and Molecular Immunology (Paperback)
Auteur
Wiegand Falkner
Éditeur
W.F
Année de publication
2026
État de l'article
new
Reliure
Paperback
Langue
anglais
ISBN à 10 chiffres
2528544499
ISBN à 13 chiffres
9782528544495

Grand Eagle Retail

Bensenville, IL, Etats-Unis

Vendeur avec une évaluation de 5 étoiles

Vendeur AbeBooks depuis 12 octobre 2005

Frais d'expédition à l'intérieur de ce pays : Etats-Unis

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