Chemokine Biology: Basic Research and Clinical Application. Vol.2

L. Gordon Letts

ISBN 10: 3764371951 / ISBN 13: 9783764371951

Edité par Springer, Basel, Birkhäuser Basel Apr 2007, 2007

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This item is printed on demand - it takes 3-4 days longer - Neuware -Chemokines play an important role in recruiting inflammatory cells into tissues in response to infection and inflammation. They also play an important role in coordinating the movement of T-cells, B-cells and dentritic cells, necessary to generate an immune response (response to injury, allergens, antigens, invading microorganisms). They selectively attract leukocytes to inflammatory foci, inducing both cell migration and activation. They are involved in various diseases, like atherosclerosis, lung and skin inflammation, multiple sclerosis, or HIV. Volume 2 of this two-volume set discusses the pathophysiology of chemokines. It is divided into two parts: a) chemokines in animal disease models, and b) chemokines as drug targets. Together with volume 1, which discusses the immunobiology of chemokines, both volumes give a comprehensive overview of chemokine biology. 168 pp. Englisch.

N° de réf. du vendeur 9783764371951

Détails bibliographiques

• Titre: Chemokine Biology: Basic Research and Clinical Application. Vol.2
• Éditeur: Springer, Basel, Birkhäuser Basel Apr 2007
• Date de parution: 2007
• Langue: anglais
• ISBN à 10 chiffres: 3764371951
• ISBN à 13 chiffres: 9783764371951
• Reliure: Buch
• État de l'article: Neu
• Dimensions: 24,4 L x 17 H x 0 P (centimètres) 24,4 centimètres de largeur par 17 centimètres de hauteur par 0 centimètres de profondeur
• Poids: 560 grammes

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Synopsis

Chemokines play an important role in recruiting inflammatory cells into tissues in response to infection and inflammation. They also play an important role in coordinating the movement of T-cells, B-cells and dentritic cells, necessary to generate an immune response (response to injury, allergens, antigens, invading microorganisms). They selectively attract leukocytes to inflammatory foci, inducing both cell migration and activation. They are involved in various diseases, like atherosclerosis, lung and skin inflammation, multiple sclerosis, or HIV.
Volume 2 of this two-volume set discusses the pathophysiology of chemokines. It is divided into two parts: a) chemokines in animal disease models, and b) chemokines as drug targets. Together with volume 1, which discusses the immunobiology of chemokines, both volumes give a comprehensive overview of chemokine biology.