Clostridioides difficile: Diagnostic and Clinical Perspectives

This book is a practical guide for clinicians and other healthcare providers on a holistic approach to understanding and managing Clostridioides difficile infection. It covers pathophysiology, the role of the microbiome, diagnostic testing, management guidelines, and treatment options, including newly approved therapeutics. It also describes the patient experience and burden of C. difficile, treatment and clinical care pathways, patient education, and economic considerations. The topics covered are based on identified real-world needs of microbiologists, clinicians, and patients and include updates on treatment and data.

Key Features:

• Provides an engaging transfer of knowledge through visual clinical decision-making tools, best practices, and patient perspectives described by thought leaders and patients
• Offers an updated method of understanding "how and why" the newest treatments work to allow the clinician the opportunity to understand how to optimize therapeutics

Glenn Tillotson, PhD, FIDSA, FCCP, is a Partner at GST Micro, a microbiologist consultant to the pharmaceutical and diagnostic industries. He provides support for both medical affairs and commercialization programs for companies, most notably in the infectious disease area.

Glenn has had a number of senior roles in the pharmaceutical industry, with over 40 years’ experience in clinical research, commercialization, and scientific communications, including publications planning, strategic drug development, life cycle management, and global launch programs.

Glenn has published over 230 articles; 5 textbook chapters; been a member of several editorial advisory boards, including Lancet Infectious Diseases; has been a member of scientific steering committees for a range of international congresses; and has been involved in several Clostridioides difficile programs. He is a fellow of Infectious Disease Society of America (IDSA) and American College of Chest Physicians and is currently Editor in Chief of the Expert Review of Anti-Infective Therapy journal.

Paul Feuerstadt, MD, FACG, AGAF, is a gastroenterologist practicing at the PACT Gastroenterology Center and is an Associate Clinical Professor of Medicine at the Yale School of Medicine.

Dr. Feuerstadt’s focuses include the microbiota, C. difficile infection, eosinophilic disorders, intestinal ischemia, and acute and chronic changes in bowel habits. He has been a principal investigator on numerous clinical trials in these spaces. Within his practice, he is very active in teaching and volunteer work locally and nationally for disease and discipline specific initiatives.

Dr. Feuerstadt has authored and coauthored many manuscripts and textbook chapters. Another passion of Dr. Feuerstadt’s is teaching, frequently giving lectures locally, regionally, nationally, and internationally. He works extensively with the gastroenterology fellows in the division of digestive disease at Yale-New Haven Hospital.

His clinical practice at the PACT Gastroenterology Center is his ultimate passion, filling the majority of his work time.

Nicolette Theriault, MPH, is a researcher and analyst in independent medical education outcomes, focusing on transforming data into actionable insights to improve medical education and patient outcomes.

She has a diverse background in health education programming, medical writing, and public health research; she brings a multidisciplinary approach to measuring impact. Nicolette has authored and coauthored multiple manuscripts in the infectious disease and medical education space.