Colon Specific Diloxanide Furoate Delivery using Microspheres

Verma, Siddharth; Shukla, Shailendra

ISBN 10: 3330039841 / ISBN 13: 9783330039841

Edité par LAP Lambert Academic Publishing, 2019

A propos de cet article

N° de réf. du vendeur I-9783330039841

Détails bibliographiques

• Titre: Colon Specific Diloxanide Furoate Delivery using Microspheres
• Éditeur: LAP Lambert Academic Publishing
• Date de parution: 2019
• Langue: anglais
• ISBN à 10 chiffres: 3330039841
• ISBN à 13 chiffres: 9783330039841
• Reliure: Couverture souple
• État de l'article: New

A propos de ce titre

Synopsis

The colon is attracting interest as a site where poorly absorbed drug molecule may have an improved bioavailability. This region of the colon is recognized as having a somewhat less hostile environment with less diversity and intensity of activity than the stomach and small intestine. Additionally, the colon has a longer retention time and appears highly responsive to agents that enhance the absorption of poorly absorbed drugs. Apart from retarding or targeting dosage forms, a reliable colonic drug delivery could also be an important starting position for the colonic absorption of per orally applied, undigested, unchanged and fully active peptide drugs.