Computer Simulations of Biomolecular Systems : Theoretical and Experimental Applications

Wilfred F. van Gunsteren

ISBN 10: 9072199251 / ISBN 13: 9789072199256

Edité par Springer Netherlands, Springer Netherlands, 1997

A propos de cet article

Druck auf Anfrage Neuware - Printed after ordering - The third volume in the series on Computer Simulation of Biomolecular Systems continues with the format introduced in the first volume [1] and elaborated in the second volume [2]. The primary emphasis is on the methodological aspects of simulations, although there are some chapters that present the results obtained for specific systems of biological interest. The focus of this volume has changed somewhat since there are several chapters devoted to structure-based ligand design, which had only a single chapter in the second volume. It seems useful to set the stage for this volume by quoting from my preface to Volume 2 [2]. 'The long-range 'goal of molecular approaches to biology is to describe living systems in terms of chemistry and physics. Over the last fifty years great progress has been made in applying the equations representing the underlying physical laws to chemical problems involv ing the structures and reactions of small molecules. Corresponding studies of mesoscopic systems have been undertaken much more recently. Molecular dynamics simulations, which are the primary focus of this volume, represent the most important theoretical approach to macromolecules of biological interest.' .

N° de réf. du vendeur 9789072199256

Détails bibliographiques

• Titre: Computer Simulations of Biomolecular Systems : Theoretical and Experimental Applications
• Éditeur: Springer Netherlands, Springer Netherlands
• Date de parution: 1997
• Langue: anglais
• ISBN à 10 chiffres: 9072199251
• ISBN à 13 chiffres: 9789072199256
• Reliure: Buch
• État de l'article: Neu
• Dimensions: 240 L x 161 H x 41 P (en millimètres) 240 millimètres de largeur par 161 millimètres de hauteur par 41 millimètres de profondeur
• Poids: 1127 grammes

A propos de ce titre

Synopsis

The third volume in the series on Computer Simulation of Biomolecular Systems continues with the format introduced in the first volume [1] and elaborated in the second volume [2]. The primary emphasis is on the methodological aspects of simulations, although there are some chapters that present the results obtained for specific systems of biological interest. The focus of this volume has changed somewhat since there are several chapters devoted to structure-based ligand design, which had only a single chapter in the second volume. It seems useful to set the stage for this volume by quoting from my preface to Volume 2 [2]. "The long-range 'goal of molecular approaches to biology is to describe living systems in terms of chemistry and physics. Over the last fifty years great progress has been made in applying the equations representing the underlying physical laws to chemical problems involv- ing the structures and reactions of small molecules. Corresponding studies of mesoscopic systems have been undertaken much more recently. Molecular dynamics simulations, which are the primary focus of this volume, represent the most important theoretical approach to macromolecules of biological interest." ...