Synopsis
Based on presentations by world-renowned investigators at the 73rd annual Cold Spring Harbor Symposium on Quantitative Biology, this volume reviews the latest advances in research on the control and regulation of stem cells. The topics covered include nuclear reprogramming, regulation of stem cell self-renewal and differentiation, the stem cell niche, and signaling and gene regulation in stem cells. Studies of embryonic stem cells and adult stem cells are covered, along with research shedding light on the roles of these cells in regeneration and cancer. Preliminary Contents: INTRODUCTION R. Jaenisch, M.T. Fuller, A. Alvarez-Buylla, and M.S. Wicha GERM CELLS AND EPIGENETICS A. Surani, G. Hannon, H. Lin, R. Martienssen, S. Yoshida, D. Solter, and U. Grossniklaus SIGNALING IN ADULT STEM CELLS R. Nusse, K.S. Zaret, H. Clevers, B.L.M. Hogan, L.I. Zon, S. Nishikawa, and T.A. Rando GENE EXPRESSION I.R. Lemischka, S.H. Orkin, R. Tjian, H.-H. Ng, K. Helin, G. Sauvageau, S. Majumder, and I. Weissman CANCER I L.F. Parada, C.J. Sherr, and J.M. Adams PLURIPOTENCY IN ES CELLS R. Young, K. Hochedlinger, T. Zwaka, G.Q. Daley, J.C. Izpisua Belmonte, and D. Melton NEURAL STEM CELLS S.J. Morrison, N. Gaiano, I. Studer, A.H. Brand, M. Maletic-Savatic, and R. McKay CANCER II J.E. Visvader, C. Kim, O.N. Witte, M.M. Shen, F.M. Watt, R.A. DePinho, and J. Rich GERM CELLS AND REGENERATION R. Lehmann, A.C. Spradling, T. Xie, A. Sánchez Alvarado, and P.A. Newmark ADULT STEM CELLS II E. Fuchs, G.M. Keller, K.R. Chien, E.M. Tanaka, M. Buckingham, A.J. Wagers, and M.A. Rudnicki NICHES AND ASYMMETRY T. Shinohara, S.L. Reiner, B. Scheres, M. Timmermans, R. Rothstein, and B.L.M. Hogan Author Index Subject Index
Présentation de l'éditeur
Based on presentations by world-renowned investigators at the 73rd annual Cold Spring Harbor Symposium on Quantitative Biology, this volume reviews the latest advances in research on the control and regulation of stem cells. The topics covered include nuclear reprogramming, regulation of stem cell self-renewal and differentiation, the stem cell niche, and signaling and gene regulation in stem cells. Studies of embryonic stem cells and adult stem cells are covered, along with research shedding light on the roles of these cells in regeneration and cancer. Preliminary Contents: INTRODUCTION R. Jaenisch, M.T. Fuller, A. Alvarez-Buylla, and M.S. Wicha GERM CELLS AND EPIGENETICS A. Surani, G. Hannon, H. Lin, R. Martienssen, S. Yoshida, D. Solter, and U. Grossniklaus SIGNALING IN ADULT STEM CELLS R. Nusse, K.S. Zaret, H. Clevers, B.L.M. Hogan, L.I. Zon, S. Nishikawa, and T.A. Rando GENE EXPRESSION I.R. Lemischka, S.H. Orkin, R. Tjian, H.-H. Ng, K. Helin, G. Sauvageau, S. Majumder, and I. Weissman CANCER I L.F. Parada, C.J. Sherr, and J.M. Adams PLURIPOTENCY IN ES CELLS R. Young, K. Hochedlinger, T. Zwaka, G.Q. Daley, J.C. Izpisua Belmonte, and D. Melton NEURAL STEM CELLS S.J. Morrison, N. Gaiano, I. Studer, A.H. Brand, M. Maletic-Savatic, and R. McKay CANCER II J.E. Visvader, C. Kim, O.N. Witte, M.M. Shen, F.M. Watt, R.A. DePinho, and J. Rich GERM CELLS AND REGENERATION R. Lehmann, A.C. Spradling, T. Xie, A. Sánchez Alvarado, and P.A. Newmark ADULT STEM CELLS II E. Fuchs, G.M. Keller, K.R. Chien, E.M. Tanaka, M. Buckingham, A.J. Wagers, and M.A. Rudnicki NICHES AND ASYMMETRY T. Shinohara, S.L. Reiner, B. Scheres, M. Timmermans, R. Rothstein, and B.L.M. Hogan Author Index Subject Index
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