Challenges arise when the size of a group of cooperating agents is scaled to hundreds or thousands of members. In domains such as space exploration, military and disaster response, groups of this size (or larger) are required to achieve extremely complex, distributed goals. This book provides extensive coverage of the latest research and novel solutions being developed in the field. It covers from specific systems, such as SERSE and WIZER, to more general approaches based on game theory, optimization, and other more theoretical frameworks.