Drug Repurposing: Exploring Newer Therapeutic Potentials

The book explores the field of drug repurposing with a focus on past trends and developments. The book delves into the repurposing of bioactive phytomolecules and their applications in various therapeutic areas, including neurological disorders, diabetes, cardiovascular diseases, and autoimmune conditions. Additionally, it addresses the pressing need for repurposing drugs to combat infectious and neglected diseases, including an in-depth analysis of drug repurposing strategies in the management of COVID-19. Throughout the chapters, readers will find case studies highlighting prominent examples of repurposed drugs, challenges related to regulatory and patent issues, and the role of computational modelling and AI in accelerating drug discovery. This essential resource showcases how drug repurposing revolutionizes modern medicine and fosters a paradigm shift in pharmaceutical research.

The book is a valuable resource for students, researchers, academicians, and pharmacologists.

?Dr. Ravinder Kaundal is working as assistant professor at NIPER Raebareli. He has done his MS (Pharm.) and Ph.D. in pharmacology and toxicology from NIPER-SAS Nagar, India. He received his postdoctoral training at Yale School of Medicine, New Haven, and Icahn School of Medicine at Mount Sinai, New York. Dr. Ravinder has made an outstanding contribution to the field of pharmacological research and has elucidated the involvement of various pathogenic pathways like oxidative stress, PARP overactivation, inflammation, and apoptosis in cerebral ischemic-reperfusion injury and diabetic neuropathy. Gene regulation is another of his interests and he has developed various tools/methods to study the mechanisms of epigenetic memory. His work is published in journals of high repute and is highly cited. He is a reviewer and editorial board member of several international journals. Also, his research interests are neuropharmacology, drug repurposing, molecular biology, ischemic-reperfusion injuries, and gene regulation.

Dr. Rahul Shukla, working as assistant professor at Department of Pharmaceutics, NIPER Raebareli, India, did Ph.D. in pharmaceutical sciences from CSIR CDRI and J.N.U New Delhi, India, M Pharm from IIT BHU, Varanasi, India and B. Pharm from Jamia Hamdard, New Delhi. He has the experience of as research scientist at Dr. Reddy's Laboratories, India, and D.S. Kothari Post-Doctoral Fellow at Panjab University, India. He has more than ten years of research and academic experience. He has more than 120 publications including 40 book chapters to his credit. He has filed 9 Patent and 1 Copyright. He was awarded SERB International Research Experience (SIRE) Fellow for the year, 2022-2023 fellowship at School of Pharmacy and Biomedical Sciences, University of Central Lancashire, United Kingdom; He also received Science and Engineering Research Board (SERB) Research Grant. His current research interests include targeted drug delivery systems, particle engineering, controlled and targeted delivery for neurodegenerative diseases and cancer and works on repurposing, particle engineering and bioavailability enhancements. 

Prof. Shubhini A. Saraf is working as director of the National Institute of Pharmaceutical Education and Research (NIPER), Raebareli (U.P.). Prior to joining NIPER, Raebareli, she was working as a professor in the Department of Pharmaceutical Sciences and Director (R&D) at Babasaheb Bhimrao Ambedkar University (A Central University), Lucknow.  Prof. Shubhini is an alumnus of the Department of Pharmaceutical Sciences, Dr. H.S. Gour University, Sagar, India. She has more than 27 years of teaching and research experience. Her research interests include nanotechnology & drug targeting as well as technology policy interventions for health care. Her work extensively discusses surface-decorated lipid nanoparticles for cancer therapy. She has 165 research papers published in journals of repute.  Prof. Shubhini has authored 07 books and 22 chapters. She has attended many national and international conferences and delivered many invited lectures. Her administrative and research work has been recognized at various national and international forums. Prof. Shubhini is a sincere administrator, academician, and researcher and is known for her inclusive involvement and untiring hard work. Her contributions to the pharmacy profession are enormous and praiseworthy.