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Earth's Mightiest Heroes and Marvel's First Family star in an intergalactic event that threatens to reshape the Marvel Universe!

Old allies make a distress call to the Avengers with news of a terrible enemy that could wipe out humanity itself. The Celestial Messiah has returned - but is Earth ready to hear his message? Meanwhile, in the most unlikely of places, the Fantastic Four witness the final conflict of the Kree/Skrull War... and a long-hidden Elder of the Universe stands revealed! With the Kree and the Skrulls united under a new emperor, their war fleet charts a course - for Earth! The Avengers are ready to fight, while the FF seek a diplomatic solution. But if the two teams can't work together to save the day, Earth may not survive...

Collecting: Empyre: Avengers #0, Empyre: Fantastic Four #0, Empyre #1-6, Empyre Epilogue