Endometrial Cancer

Earl A. Surwit

ISBN 10: 1461282101 / ISBN 13: 9781461282105

Edité par Springer, Chapman And Hall/CRC Sep 2011, 2011

A propos de cet article

This item is printed on demand - it takes 3-4 days longer - Neuware -The incidence of endometrial cancer rose sharply in the United States in the early 1970s, paralleling changes in the use of postmenopausal estrogens by American women. A sizeable body of evidence supports the role of both excessive endogenous estrogen and exogenous estrogen in the etiology of endometrial cancer. There is growing evidence that inadequate progesterone has the opposite effect, in that progesterone supplementation of postmeno pausal estrogen therapy reduces the incidence of endometrial cancer. Despite this new awareness of the hormonal role that is played in carcino ma of the endometrium, the disease still plagues the oncologist. The general approach to carcinoma of the endometrium in the United States is that of primary surgical staging. This provides the maximum amount of information to best plan postoperative radiation therapy and/or chemotherapy for these patients. In general, patients who are considered candidates for surgical staging are those with advanced disease or high-risk stage I endometrial carcinoma. High-risk endometrial carcinoma is defined as those patients with moderately differentiated lesions with deep myometrial invasion, poor ly differentiated carcinoma of the endometrium, and the high-risk histolo gies such as papillary carcinoma and clear-cell carcinomas. The surgical staging has extended in most institutions to patients with occult stage II carcinoma of the endometrium, i. e. 152 pp. Englisch.

N° de réf. du vendeur 9781461282105

Détails bibliographiques

• Titre: Endometrial Cancer
• Éditeur: Springer, Chapman And Hall/CRC Sep 2011
• Date de parution: 2011
• Langue: anglais
• ISBN à 10 chiffres: 1461282101
• ISBN à 13 chiffres: 9781461282105
• Reliure: Taschenbuch
• État de l'article: Neu
• Dimensions: 235 L x 155 H x 9 P (en millimètres) 235 millimètres de largeur par 155 millimètres de hauteur par 9 millimètres de profondeur
• Poids: 242 grammes

A propos de ce titre

Synopsis

The incidence of endometrial cancer rose sharply in the United States in the early 1970s, paralleling changes in the use of postmenopausal estrogens by American women. A sizeable body of evidence supports the role of both excessive endogenous estrogen and exogenous estrogen in the etiology of endometrial cancer. There is growing evidence that inadequate progesterone has the opposite effect, in that progesterone supplementation of postmeno- pausal estrogen therapy reduces the incidence of endometrial cancer. Despite this new awareness of the hormonal role that is played in carcino- ma of the endometrium, the disease still plagues the oncologist. The general approach to carcinoma of the endometrium in the United States is that of primary surgical staging. This provides the maximum amount of information to best plan postoperative radiation therapy and/or chemotherapy for these patients. In general, patients who are considered candidates for surgical staging are those with advanced disease or high-risk stage I endometrial carcinoma. High-risk endometrial carcinoma is defined as those patients with moderately differentiated lesions with deep myometrial invasion, poor- ly differentiated carcinoma of the endometrium, and the high-risk histolo- gies such as papillary carcinoma and clear-cell carcinomas. The surgical staging has extended in most institutions to patients with occult stage II carcinoma of the endometrium, i. e.