O fl�or desempenha um papel significativo na sa�de dent�ria e esquel�tica. Tem sido amplamente estudado e debatido. Embora o fl�or em concentra��es adequadas seja ben�fico, a ingest�o excessiva de fl�or, especialmente em crian�as, pode levar a problemas de sa�de graves, como a fluorose dent�ria, a fluorose esquel�tica e a fluorose n�o esquel�tica. A sobre-exposi��o a longo prazo ao fl�or, particularmente em �reas end�micas, tem sido associada a uma s�rie de efeitos adversos para a sa�de, incluindo a neurotoxicidade, que afecta o desenvolvimento da intelig�ncia nas crian�as. O QI � uma medida de intelig�ncia derivada de testes padronizados. V�rios estudos efectuados em todo o mundo demonstraram consistentemente uma rela��o inversa entre a exposi��o ao fl�or e os n�veis de QI das crian�as. Embora as provas sugiram uma associa��o entre a exposi��o ao fl�or e um QI mais baixo, estas conclus�es s�o inconclusivas e n�o generaliz�veis. O QI � influenciado por m�ltiplos factores, que n�o foram adequadamente avaliados nestes estudos. Para estabelecer uma rela��o causal, precisamos de estudos longitudinais que controlem estes factores de confus�o para melhor compreender e mitigar o potencial impacto do fl�or na intelig�ncia.

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