Fluoroquinolone Antibiotics

Donald Low

ISBN 10: 3764365919 / ISBN 13: 9783764365912

Edité par Birkhäuser Basel, Birkhäuser Basel Apr 2003, 2003

A propos de cet article

Neuware -Since the introduction of ciprofloxacin in 1987, fluoroquinolones have expanded far beyond their early role in the treatment of urinary tract infections. Clinical applications beyond genitourinary tract infections include upper and lower respiratory infections, gastrointestinal infections, gynecologic infec tions, sexually transmitted diseases, and some skin and soft tissue infections. Their ease of administration, favorable pharmacokinetic properties, excellent tolerability, and efficacy give them enormous potential for use and misuse alike. Quinolones have few common adverse effects, most notably nausea, headache and dizziness. Less frequent but more serious adverse events include prolongation of the corrected QT interval, phototoxicity, liver enzyme abnor malities, arthropathy, and cartilage and tendon abnormalities. While possess ing many of the favorable properties of intravenous agents, most fluoro quinolones offer the convenience of oral administration, thus contributing to decreased health-care costs through increased outpatient therapy and short ened hospital stays. With the recent introduction of agents such as gatifloxacin and moxifloxacin, the traditional Gram-negative coverage of fluoroquinolones has been expanded to include Gram-positive organisms, most importantly Streptococcus pneumoniae.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 276 pp. Englisch.

N° de réf. du vendeur 9783764365912

Détails bibliographiques

• Titre: Fluoroquinolone Antibiotics
• Éditeur: Birkhäuser Basel, Birkhäuser Basel Apr 2003
• Date de parution: 2003
• Langue: anglais
• ISBN à 10 chiffres: 3764365919
• ISBN à 13 chiffres: 9783764365912
• Reliure: Buch
• État de l'article: Neu
• Dimensions: 241 L x 160 H x 20 P (en millimètres) 241 millimètres de largeur par 160 millimètres de hauteur par 20 millimètres de profondeur
• Poids: 582 grammes

A propos de ce titre

Synopsis

Since the introduction of ciprofloxacin in 1987, fluoroquinolones have expanded far beyond their early role in the treatment of urinary tract infections. Clinical applications beyond genitourinary tract infections include upper and lower respiratory infections, gastrointestinal infections, gynecologic infec- tions, sexually transmitted diseases, and some skin and soft tissue infections. Their ease of administration, favorable pharmacokinetic properties, excellent tolerability, and efficacy give them enormous potential for use and misuse alike. Quinolones have few common adverse effects, most notably nausea, headache and dizziness. Less frequent but more serious adverse events include prolongation of the corrected QT interval, phototoxicity, liver enzyme abnor- malities, arthropathy, and cartilage and tendon abnormalities. While possess- ing many of the favorable properties of intravenous agents, most fluoro- quinolones offer the convenience of oral administration, thus contributing to decreased health-care costs through increased outpatient therapy and short- ened hospital stays. With the recent introduction of agents such as gatifloxacin and moxifloxacin, the traditional Gram-negative coverage of fluoroquinolones has been expanded to include Gram-positive organisms, most importantly Streptococcus pneumoniae.