The Genetics of Obesity

Langue : anglais

Edité par Springer, 2014

1461486416 / 9781461486411

Vendeur : killarneybooks, Inagh, Clare, Irlandekillarneybooks

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A propos de cet article

Hardcover, viii + 128 pages, NOT ex-library. Interior is clean and bright throughout, with unmarked text, free of inscriptions and stamps, securely bound. Minor wear to tips of page corners. Boards are moderately bent / crooked (do not align correctly), with creases and small indentations to edges, faint shelfwear. Issued without a dust jacket. -- Contents: Genetic Variation and Obesity Prior to the Era of Genome-Wide Association Studies; Genetic Obesity Syndromes; Genome-Wide Association Studies of Obesity; Copy Number Variants and their Contribution to the Risk of Obesity; Genetics of Childhood Obesity; Genetic Pleiotropies of Obesity; Functional Follow-up of Genetic Variants Using FTO as the Prime Example; Index -- "In the past four years, many genetic loci have been implicated for BMI from the outcomes of genome-wide association studies (GWAS), primarily in adults. Insulin-induced gene 2 (INSIG2) was the first locus to be reported by this method to have a role in obesity but replication attempts have yielded inconsistent outcomes. The identification of the second locus, the fat mass- and obesity-associated gene (FTO), h has been more robustly observed by others. Studies from both FTO knock out and FTO overexpression mouse model support the fact that FTO is directly involved in the regulation of energy intake and metabolism in mice, where the lack of FTO expression leads to leanness while enhanced expression of FTO leads to obesity. Along with numerous other studies, a number of genetic variants have been established robustly in the context of obesity, giving us fresh insights into the pathogenesis of the disease. This book will give a comprehensive overview of efforts aimed at uncovering genetic variants associated with obesity, which have been particularly successful in the past 5 years with the advent of genome-wide association studies (GWAS). This book will cover this state of the art technology and its application to obesity in great detail. Topics covered will include genetics of childhood obesity, genetics of syndromic obesity, copy number variants and extreme obesity, co-morbidities of obesity genetics, and functional follow-up of genetic variants.​".…

N° de réf. du vendeur 005690

Titre
The Genetics of Obesity
Auteur
Struan F.A. Grant
Éditeur
Springer
Année de publication
2014
État de l'article
Good
Reliure
Hardcover
Langue
anglais
ISBN à 10 chiffres
1461486416
ISBN à 13 chiffres
9781461486411

killarneybooks

Inagh, Clare, Irlande

Vendeur avec une évaluation de 5 étoiles

Vendeur AbeBooks depuis 20 avril 2017

Frais d'expédition de Irlande vers Etats-Unis

Article6 à 7 jours ouvrés3 à 4 jours ouvrés
Premier articleEUR 33,70EUR 38,00
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All U.S.-bound orders are now shipped with UPS for reliable delivery. Additional customs or import fees are highly unlikely; however, please note buyers remain responsible for any duties or taxes that U.S. Customs may assess. -- Killarneybooks is a family-run bookshop based in the Republic of Ireland. We take pride in accurate listings, careful packaging, and prompt service - most orders ship within 24 hours. All books listed are in stock and ready for immediate dispatch - we are not dropshippers. Inquiries always welcome.…

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professional, academic, non-fiction