Handbook of Cancer Models with Applications (Mathematical Biology and Medicine)

ISBN 10: 9812779477 / ISBN 13: 9789812779472

Edité par World Scientific Publishing Comp, 2008

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Détails bibliographiques

Titre : Handbook of Cancer Models with Applications ...

Éditeur : World Scientific Publishing Comp

Date d'édition : 2008

Reliure : hardcover

Etat : Very Good

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Synopsis :

Composed of contributions from an international team of leading researchers, this book pulls together the most recent research results in the field of cancer modeling to provide readers with the most advanced mathematical models of cancer and their applications.Topics included in the book cover oncogenetic trees, stochastic multistage models of carcinogenesis, effects of ionizing radiation on cell cycle and genomic instability, induction of DNA damage by ionizing radiation and its repair, epigenetic cancer models, bystander effects of radiation, multiple pathway models of human colon cancer, and stochastic models of metastasis. The book also provides some important applications of cancer models to the assessment of cancer risk associated with various hazardous environmental agents, to cancer screening by MRI, and to drug resistance in cancer chemotherapy. An updated statistical design and analysis of xenograft experiments as well as a statistical analysis of cancer occult clinical data are also provided.The book will serve as a useful source of reference for researchers in biomathematics, biostatistics and bioinformatics; for clinical investigators and medical doctors employing quantitative methods to develop procedures for cancer diagnosis, prevention, control and treatment; and for graduate students.