Handbook of Single-Molecule Biophysics

Antoine van Oijen

ISBN 10: 149393919X / ISBN 13: 9781493939190

Edité par Springer New York, Springer US, 2016

A propos de cet article

Druck auf Anfrage Neuware - Printed after ordering - During the last decade, a number of novel biophysical methods have been developed that allow the manipulation and study of individual biomolecules. The ability to monitor biological processes at the fundamental level of sensitivity, that of a single molecule, has given rise to an improved understanding of the underlying molecular mechanisms. Through the removal of ensemble averaging, distributions and fluctuations of molecular properties can be characterized, transient intermediates identified, and catalytic mechanisms elucidated. By applying forces on biomolecules while monitoring their activity, important information can be obtained on how proteins couple function to structure. The Handbook of Single-Molecule Biophysics provides an introduction to these techniques and presents an extensive discussion of the new biological insights obtained from them.Editorial Advisory Board: Daniel Müller, Cheng Zhu, Claus Seidel, Xiaowei Zhuang, Thomas Schmidt, Nynke Dekker.

N° de réf. du vendeur 9781493939190

Détails bibliographiques

• Titre: Handbook of Single-Molecule Biophysics
• Éditeur: Springer New York, Springer US
• Date de parution: 2016
• Langue: anglais
• ISBN à 10 chiffres: 149393919X
• ISBN à 13 chiffres: 9781493939190
• Reliure: Taschenbuch
• État de l'article: Neu
• Dimensions: 235 L x 155 H x 33 P (en millimètres) 235 millimètres de largeur par 155 millimètres de hauteur par 33 millimètres de profondeur
• Poids: 1091 grammes

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Synopsis

During the last decade, a number of novel biophysical methods have been developed that allow the manipulation and study of individual biomolecules. The ability to monitor biological processes at the fundamental level of sensitivity, that of a single molecule, has given rise to an improved understanding of the underlying molecular mechanisms. Through the removal of ensemble averaging, distributions and fluctuations of molecular properties can be characterized, transient intermediates identified, and catalytic mechanisms elucidated. By applying forces on biomolecules while monitoring their activity, important information can be obtained on how proteins couple function to structure. The Handbook of Single-Molecule Biophysics provides an introduction to these techniques and presents an extensive discussion of the new biological insights obtained from them.

Editorial Advisory Board: Daniel Müller, Cheng Zhu, Claus Seidel, Xiaowei Zhuang, Thomas Schmidt, Nynke Dekker.