Hepatitis B and D Protocols

. Ed(s): Hamatake, Robert K.; Lau, Johnson Y. N.

ISBN 10: 1588291081 / ISBN 13: 9781588291080

Edité par Humana Press Inc., 2004

This work discusses the significant worldwide health burden of hepatitis B virus (HBV) and hepatitis delta virus (HDV) in two volumes; reviews research techniques used in the study of HBV and HDV; and provides detailed descriptions of techniques that can be easily reproduced. Editor(s): Hamatake, Robert K.; Lau, Johnson Y. N. Series: Methods in Molecular Medicine. Num Pages: 572 pages, biography. BIC Classification: MMFM. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 32. Weight in Grams: 1162. . 2004. Hardback. . . . . Books ship from the US and Ireland. N° de réf. du vendeur V9781588291080

Synopsis :

Despite the availability of an effective vaccine, there are still 400 million people, worldwide who are chronically infected with hepatitis B virus (HBV). For them, the vaccine, as currently applied, has no value. Given the possible consequences of HBV infection, the number of those chronically infected with HBV presents an enormous public health challenge. For example, the major etiology of hepatocellular carcinoma (HCC) is chronic infection with HBV. Although fifth in cancer incidence, worldwide, HCC/liver cancer is the third leading cause of cancer death. The high mortality as- ciated with HCC arises because the disease is often detected late and is unresponsive to treatment. The number of deaths caused by PHCC is expected to rise over the next 20 years. Those chronically infected with HBV have a life risk of death to HCC of between 10 and 25%. Even the limited efficacy of drugs for the treatment of chronic HBV helps underscore the point that this disease is responsive to therapy. Drugs that target the polymerase (e. g., hepsera and lamivudine) and interferon alpha represent two distinct strategies and show that both conventional antiviral and immunothe- peutic approaches can be used in management. However, the current inventory of therapeutics is inadequate. Interferon alpha is of limited value, only parenterally ava- able, and fraught with adverse reactions.

Détails bibliographiques

Titre : Hepatitis B and D Protocols
Éditeur : Humana Press Inc.
Date d'édition : 2004
Reliure : Couverture rigide
Etat : New