The Immune Synapse as a Novel Target for Therapy

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ISBN 10: 3764382953 ISBN 13: 9783764382957

Edit� par Birkh?user, 2007

Neuf(s) Couverture rigide

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2007. Hardcover. . . . . . Books ship from the US and Ireland. N� de r�f. du vendeur V9783764382957

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It is now accepted that T cell activation by an antigen-presenting cell requires the organization of a supramolecular structure - the immune synapse. This structure, with different types of molecules spatially segregated, is involved in the delivery of quantitative and qualitative signals critical for T cell activation, and therefore in controlling the nature of the immune response. This volume discusses the progress in manipulating components of the immune synapse as a strategy to regulate the immune response in immune pathology, such as transplantation, autoimmunity and allergy. Donnadieu reviews the current knowledge on the molecular composition and organization of the immune synapse and how the formation of this structure can be modulated by chemokines. It is also known that the immune synapse formation is critical for the activation of naive T cells, as well as their functional polarization. The second chapter discusses the conversion of naive T cells into regulatory T cells (Treg) when components of the immune synapse are manipulated in such a way that the T cells receive suboptimal activation signals.

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Titre : The Immune Synapse as a Novel Target for ...
�diteur : Birkh?user
Date d'�dition : 2007
Reliure : Couverture rigide
Etat : New

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The Immune Synapse as a Novel Target for Therapy (Progress in Inflammation Research Series)

Luis Graca

Edit� par Birkhauser, Switzerland, 2007

ISBN 10 : 3764382953 ISBN 13 : 9783764382957

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Hardcover. Etat : Near Fine. 9783764382957. Pictorial board hardcover, from closed pharmaceutical company library. 196 pages, index, illustrated with charts, tables and diagrams. An overview on the progress in immune synapse research, from basic science to clinical trials, and the major mechanisms involved. Discusses how interfering with T cell activation may lead to immune tolerance, immune modulation, and the recruitment of regulatory T cells; the role of monoclonal antibodies in tolerance induction; and mechanisms maintaining dominant tolerance. Contents as new, clean, tight and bright. Book. N� de r�f. du vendeur 029530

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The Immune Synapse as a Novel Target for Therapy

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Edit� par Birkh�user, 2007

ISBN 10 : 3764382953 ISBN 13 : 9783764382957

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Etat : Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: B�cher | It is now accepted that T cell activation by an antigen-presenting cell requires the organization of a supramolecular structure � the immune synapse. This structure, with different types of molecules spatially segregated, is involved in the delivery of quantitative and qualitative signals critical for T cell activation, and therefore in controlling the nature of the immune response. This volume discusses the progress in manipulating components of the immune synapse as a strategy to regulate the immune response in immune pathology, such as transplantation, autoimmunity and allergy. Donnadieu reviews the current knowledge on the molecular composition and organization of the immune synapse and how the formation of this structure can be modulated by chemokines. It is also known that the immune synapse formation is critical for the activation of naive T cells, as well as their functional polarization. The second chapter discusses the conversion of naive T cells into regulatory T cells (Treg) when components of the immune synapse are manipulated in such a way that the T cells receive suboptimal activation signals. N� de r�f. du vendeur 3940306/2

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The Immune Synapse as a Novel Target for Therapy

Graca, Luis

Edit� par Birkh�user Basel, 2007

ISBN 10 : 3764382953 ISBN 13 : 9783764382957

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Gebunden. Etat : New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Discusses how interfering with T cell activation may lead to immune toleranceDescribes immune modulation and the recruitment of regulatory T cellsProvides information on the role of monoclonal antibodies in tolerance inductionDescrib. N� de r�f. du vendeur 449594091

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The Immune Synapse as a Novel Target for Therapy

Luis Graca

Edit� par Birkh�user, 2007

ISBN 10 : 3764382953 ISBN 13 : 9783764382957

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The Immune Synapse as a Novel Target for Therapy

Luis Graca

Edit� par Birkh�user, Birkh�user Okt 2007, 2007

ISBN 10 : 3764382953 ISBN 13 : 9783764382957

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Buch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -It is now accepted that T cell activation by an antigen-presenting cell requires the organization of a supramolecular structure � the immune synapse. This structure, with different types of molecules spatially segregated, is involved in the delivery of quantitative and qualitative signals critical for T cell activation, and therefore in controlling the nature of the immune response. This volume discusses the progress in manipulating components of the immune synapse as a strategy to regulate the immune response in immune pathology, such as transplantation, autoimmunity and allergy. Donnadieu reviews the current knowledge on the molecular composition and organization of the immune synapse and how the formation of this structure can be modulated by chemokines. It is also known that the immune synapse formation is critical for the activation of naive T cells, as well as their functional polarization. The second chapter discusses the conversion of naive T cells into regulatory T cells (Treg) when components of the immune synapse are manipulated in such a way that the T cells receive suboptimal activation signals.Springer Nature c/o IBS, Benzstrasse 21, 48619 Heek 212 pp. Englisch. N� de r�f. du vendeur 9783764382957

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The Immune Synapse as a Novel Target for Therapy

Luis Graca

Edit� par Birkh�user Basel, Birkh�user, 2007

ISBN 10 : 3764382953 ISBN 13 : 9783764382957

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Buch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - It is now accepted that T cell activation by an antigen-presenting cell requires the organization of a supramolecular structure - the immune synapse. This structure, with different types of molecules spatially segregated, is involved in the delivery of quantitative and qualitative signals critical for T cell activation, and therefore in controlling the nature of the immune response. This volume discusses the progress in manipulating components of the immune synapse as a strategy to regulate the immune response in immune pathology, such as transplantation, autoimmunity and allergy. Donnadieu reviews the current knowledge on the molecular composition and organization of the immune synapse and how the formation of this structure can be modulated by chemokines. It is also known that the immune synapse formation is critical for the activation of naive T cells, as well as their functional polarization. The second chapter discusses the conversion of naive T cells into regulatory T cells (Treg) when components of the immune synapse are manipulated in such a way that the T cells receive suboptimal activation signals. N� de r�f. du vendeur 9783764382957

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The Immune Synapse as a Novel Target for Therapy

Luis Graca

Edit� par Springer, Basel, Birkh�user Basel Okt 2007, 2007

ISBN 10 : 3764382953 ISBN 13 : 9783764382957

Neuf Couverture rigide

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Vendeur : BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Allemagne

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Buch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It is now accepted that T cell activation by an antigen-presenting cell requires the organization of a supramolecular structure - the immune synapse. This structure, with different types of molecules spatially segregated, is involved in the delivery of quantitative and qualitative signals critical for T cell activation, and therefore in controlling the nature of the immune response. This volume discusses the progress in manipulating components of the immune synapse as a strategy to regulate the immune response in immune pathology, such as transplantation, autoimmunity and allergy. Donnadieu reviews the current knowledge on the molecular composition and organization of the immune synapse and how the formation of this structure can be modulated by chemokines. It is also known that the immune synapse formation is critical for the activation of naive T cells, as well as their functional polarization. The second chapter discusses the conversion of naive T cells into regulatory T cells (Treg) when components of the immune synapse are manipulated in such a way that the T cells receive suboptimal activation signals. 192 pp. Englisch. N� de r�f. du vendeur 9783764382957

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