Interaction of Nanomaterials With Living Cells

This book examines the interactions of nanomaterials with the biological system. The chapters of the book explore the natural and synthetic biomaterials that modulate immune responses for their applications in drug delivery and tissue engineering. Further, the book discusses the implications of the physiochemical properties of nanoparticles and their microenvironment on their interactions with biological systems. The chapters also present the recognitive capabilities of biomaterials for the development of novel strategies for the detection and treatment of autoimmune disorders. The book also introduces nanotechnology platforms for drug delivery and highlights current and emerging nanotechnologies that could enable novel classes of therapeutics. Towards the end, the book reviews the efficiency of drug-loaded nanoparticles in modulating the functioning of the biological milieu for improved disease treatment. Lastly, the book outlines the ethical issues regarding the use of nanoparticles for in vitro and in vivo applications. Given its scope, it is a valuable resource for graduate students and researchers interested in understanding the biomedical applications of nanoparticles and their interactions with the biological milieu.

Dr. Faheem Arjamend Sheikh is an Assistant Professor at the Department of Nanotechnology, University of Kashmir, India (2015). He served as an Assistant Professor at the Department of Biotechnology at the Central University of Kashmir, India (2015-2016); Assistant Professor of Research at Myongji University, South Korea (2014-2015); Research Professor at Hallym University, South Korea (2012-2014); Post-Doc/Research fellow at the University of Texas Rio Grande Valley, Texas, United States of America (2010-2012) and Research Professor at Myongji University, South Korea (2010). His research mainly focuses on fabricating nanomaterials used in tissue engineering.

Currently, he is heading a lab, which works on creating different nanomaterials that can be used in various biological applications; this includes cell culturing and microbial assays. He has considerable expertise in the fabrication of polymeric, ceramic, and metal oxide nanofibers using electrospinning, as well as the production of porous materials by solvent casting, salt-leaching, 3D printing, gas forming, sol-gel synthesis, phase separation, freeze-drying, and particulate leaching and self-assembly for hard and soft tissue engineering. He has more than 16 years of research experience, focusing on tissue engineering and drug delivery. He has published more than 100 peer-reviewed articles and book chapters.

Dr. Shafquat Majeed is currently working as an Assistant Professor in the Department of Nanotechnology, University of Kashmir, India. Dr. Majeed did his Masters's in Chemistry from the Department of Chemistry, University of Kashmir. He did his Ph.D. from the Indian Institute of Science Bangalore (2008-2015). He has a postdoctoral research experience in rare-earth-based nanomaterials for biomedical applications and fabrication of Perovskite-based solar cells from the Centre for Nanoscience and Engineering, IISc Bangalore (2015-2016).

Presently, he heads a Multifunctional Nanomaterials Laboratoryat the University of Kashmir where the research group works on the synthesis, characterization, optical and magnetic properties of nanomaterials prepared through various solution-based routes.

Dr. Mushtaq A. Beigh is working as an Assistant Professor at the Department of Nanotechnology, University of Kashmir, India. Dr. Beigh has postdoctoral research experience in cellular signaling and disease modeling (2013-2016). He had completed his Ph.D. from the University of Kashmir, India (2008-2012). He heads a laboratory at the University of Kashmir, where they work on a bio-nano interface to understand the molecular basis of nanoconjugate internalization. They are working to understand the growth factor signaling inputs directed at multiple cellular receptors like NRP1 and Integrins to work out the mechanistic details of receptor-based internalization.