Intrinsic Immunity (Current Topics in Microbiology and Immunology, 371)

ISBN 10: 3642427634 ISBN 13: 9783642427633

Edit� par Springer, 2015

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Synopsis :

Recent research has focused attention on the importance of intrinsic antiviral immunity, i.e. immunity mediated by factors that are constitutively expressed in many cells. In this volume, leading experts provide a comprehensive overview of this relatively new and rapidly evolving field. They cover intrinsic proteinaceous antiviral immune effectors, such as the APOBEC3 and TRIM protein families as well as Tetherin and SAMHD1, which were initially discovered by researchers studying HIV-1. Furthermore, the role of RNA interference in antiviral defense in plants and invertebrates, as well as the interplay between microRNAs and viruses in mammalian cells, are analysed. One chapter discusses how intrinsic immunity and viral countermeasures to intrinsic immune effectors drive both pathogen and host evolution, and finally the emerging evidence that DNA damage response proteins restrict infection by DNA viruses is highlighted.

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Titre : Intrinsic Immunity (Current Topics in ...
�diteur : Springer
Date d'�dition : 2015
Reliure : Couverture souple
Etat : New

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Intrinsic Immunity (Current Topics in Microbiology and Immunology, 371) [Paperback] Cullen, Bryan R. (eng)

Cullen, Bryan R.

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Intrinsic Immunity

Cullen, Bryan R.

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Intrinsic Immunity

Bryan R. Cullen

Edit� par Springer Berlin Heidelberg Jun 2015, 2015

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Taschenbuch. Etat : Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Recent research has focused attention on the importance of intrinsic antiviral immunity, i.e. immunity mediated by factors that are constitutively expressed in many cells. In this volume, leading experts provide a comprehensive overview of this relatively new and rapidly evolving field. They cover intrinsic proteinaceous antiviral immune effectors, such as the APOBEC3 and TRIM protein families as well as Tetherin and SAMHD1, which were initially discovered by researchers studying HIV-1. Furthermore, the role of RNA interference in antiviral defense in plants and invertebrates, as well as the interplay between microRNAs and viruses in mammalian cells, are analysed. One chapter discusses how intrinsic immunity and viral countermeasures to intrinsic immune effectors drive both pathogen and host evolution, and finally the emerging evidence that DNA damage response proteins restrict infection by DNA viruses is highlighted. 272 pp. Englisch. N� de r�f. du vendeur 9783642427633

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Intrinsic Immunity

Bryan R. Cullen

Edit� par Springer Berlin Heidelberg, Springer Berlin Heidelberg Jun 2015, 2015

ISBN 10 : 3642427634 ISBN 13 : 9783642427633

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Taschenbuch. Etat : Neu. This item is printed on demand - Print on Demand Titel. Neuware -Recent research has focused attention on the importance of intrinsic antiviral immunity, i.e. immunity mediated by factors that are constitutively expressed in many cells. In this volume, leading experts provide a comprehensive overview of this relatively new and rapidly evolving field. They cover intrinsic proteinaceous antiviral immune effectors, such as the APOBEC3 and TRIM protein families as well as Tetherin and SAMHD1, which were initially discovered by researchers studying HIV-1. Furthermore, the role of RNA interference in antiviral defense in plants and invertebrates, as well as the interplay between microRNAs and viruses in mammalian cells, are analysed. One chapter discusses how intrinsic immunity and viral countermeasures to intrinsic immune effectors drive both pathogen and host evolution, and finally the emerging evidence that DNA damage response proteins restrict infection by DNA viruses is highlighted.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 272 pp. Englisch. N� de r�f. du vendeur 9783642427633

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Intrinsic Immunity

Bryan R. Cullen

Edit� par Springer Berlin Heidelberg, 2015

ISBN 10 : 3642427634 ISBN 13 : 9783642427633

Neuf Taschenbuch

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Taschenbuch. Etat : Neu. Druck auf Anfrage Neuware - Printed after ordering - Recent research has focused attention on the importance of intrinsic antiviral immunity, i.e. immunity mediated by factors that are constitutively expressed in many cells. In this volume, leading experts provide a comprehensive overview of this relatively new and rapidly evolving field. They cover intrinsic proteinaceous antiviral immune effectors, such as the APOBEC3 and TRIM protein families as well as Tetherin and SAMHD1, which were initially discovered by researchers studying HIV-1. Furthermore, the role of RNA interference in antiviral defense in plants and invertebrates, as well as the interplay between microRNAs and viruses in mammalian cells, are analysed. One chapter discusses how intrinsic immunity and viral countermeasures to intrinsic immune effectors drive both pathogen and host evolution, and finally the emerging evidence that DNA damage response proteins restrict infection by DNA viruses is highlighted. N� de r�f. du vendeur 9783642427633

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