Mathematical Modelling of Granulation Processes

Patrick Rynhart

ISBN 10: 3639019776 ISBN 13: 9783639019773
Edité par VDM Verlag Dr. Müller, 2009
Neuf(s) Taschenbuch

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Mathematical Modelling of Granulation Processes | Patrick Rynhart | Taschenbuch | Einband - flex.(Paperback) | Englisch | 2009 | VDM Verlag Dr. Müller | EAN 9783639019773 | Verantwortliche Person für die EU: OmniScriptum GmbH & Co. KG, Bahnhofstr. 28, 66111 Saarbrücken, info[at]akademikerverlag[dot]de | Anbieter: preigu. N° de réf. du vendeur 101646789

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This thesis studies wet granulation on three different levels. First, micro-level investigations of liquid bridges between two and three particles are performed. For the two-particle case, the fluid profile of static (stationary) and dynamic (moving) liquid bridges are investigated. Static liquid bridges between three equally sized primary particles are then studied; the symmetry of the problem is used to obtain a numerical solution to the Young-Laplace equation. Secondly, a model to estimate the stickiness (fractional wet surface area) of agglomerates is proposed. The model includes parameters to control the inter-particle separation distance and the fluid saturation state. Computational geometry is used to obtain results which relate the number of particles and the volume of binder fluid to the stickiness of the agglomerates. Finally, a population balance model for wet granulation is developed by extending an earlier model to incorporate the effects of binder fluid. The model is solved numerically for a range of coalescence kernels and results are presented which show the effect of binder volume and the drying rate.

Présentation de l'éditeur: This thesis studies wet granulation on three different levels. First, micro-level investigations of liquid bridges between two and three particles are performed. For the two-particle case, the fluid profile of static (stationary) and dynamic (moving) liquid bridges are investigated. Static liquid bridges between three equally sized primary particles are then studied; the symmetry of the problem is used to obtain a numerical solution to the Young-Laplace equation. Secondly, a model to estimate the stickiness (fractional wet surface area) of agglomerates is proposed. The model includes parameters to control the inter-particle separation distance and the fluid saturation state. Computational geometry is used to obtain results which relate the number of particles and the volume of binder fluid to the stickiness of the agglomerates. Finally, a population balance model for wet granulation is developed by extending an earlier model to incorporate the effects of binder fluid. The model is solved numerically for a range of coalescence kernels and results are presented which show the effect of binder volume and the drying rate.

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Détails bibliographiques

Titre : Mathematical Modelling of Granulation ...
Éditeur : VDM Verlag Dr. Müller
Date d'édition : 2009
Reliure : Taschenbuch
Etat : Neu

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