Medicinal Chemistry : A Series of Monographs: Vol: 11: Drug Design ( Part 1 to 10 Set)

Edité par Academic Press for Elsevier, Noida, 2009

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Contents Vol. I. Preface. 1. A general introduction to the field of drug design/E.J. Ariens. 2. Quantitative structure activity relationships in drug design/Corwin Hansch. 3. Physicochemical approaches to the rational development of new drugs/J.K. Seydel. 4. A molecular orbital approach to quantitative drug design/A.J. Wohl. 5. Electronic aspects of drug action/Roger L. Schnaare. 6. The role of biopharmaceutics in the design of drug products/John G. Wagner. 7. Significance of pharmacokinetics for drug design and the planning of dosage regimens/J.M. van Rossum. Author index. Subject index. Vol. II. Preface. 1. Modulation of pharmacokinetics by molecular manipulation/E.J. Ariens. 2. Factors in the design of reversible and irreversible enzyme inhibitors/Howard J. Schaeffer. 3. The design of organophosphate and carbamate inhibitors of cholinesterases/R.D. O'Brien. 4. The design of reactivators for irreversibly blocked acetylcholinesterase/I.B. Wilson and Harry C. Froede. 5. Inhibition of protein biosynthesis its significance in drug design/Arthur P. Grollman. 6. Enzymes and their synthesis as a target for antibiotic action/M.H. Richmond. 7. The rational design of antiviral agents/Arthur P. Grollman and Susan B. Horwitz. 8. Design of penicillins/A.E. Bird and J.H.C. Nayler. 9. The design of peptide hormone analogs/J. Rudinger. 10. Recent advances in the design of diuretics/George de Stevens. 11. Design of biologically active steroids/G.A. Overbeek J. van der Vies and J. de Visser. 12. Rational elements in the development of superior neuromuscular blocking agents/M. Martin Smith. 13. The design of tumor inhibitory alkylating drugs/J.A. Stock. Author index. Subject index. Vol. III. Preface. 1. Microbial conversion as a tool in the preparation of drugs/R. Beukers A.F. Marx and M.H.J. Zuldweg. 2. The use of linear free energy parameters and other experimental constants in structure activity studies/A. Verloop. 3. Anticoagulants structurally and functionally related to vitamin K/T. Kralt and V. Claassen. 4. Design of B blocking drugs/A.M. Barrett. 5. The design of biologically active acridines/Adrien Albert. 6. The design of local anesthetics/J. Buchi and X. Perlia. 7. Design of insect chemosterilants/Ralph B. Turner. 8. Molecular approach for designing inhibitors to enzymes involved in blood clotting/L. Lorand and J.L.G. Nilsson. Author index. Subject index. Vol. IV. Preface. 1. Biopharmaceutics as a basis for the design of drug products/Leslie Z. Benet. 2. Peroral solid dosage forms with prolonged action/W.A. Ritschel. 3. Parenteral dosage forms with prolonged action/W.A. Ritschel. 4. Design of topical drug products pharmaceutics/Martin Katz. 5. Design of topical drug products biopharmaceutics/Boyd J. Poulsen. 6. The design of sunscreen preparations/Goswin W. van Ham and Wolfgang P. Herzog. 7. Litholytic agents preventive and curative drugs for nephrolithiasis/George Kallistratos. 8. The design of biologically active nucleosides/Alexander Bloch. 9. The design of insecticidal chlorohydrocarbon derivatives/G.T. Brooks. Author index. Subject index. Vol. V. Preface. 1. Utilization of operational schemes for analog synthesis in drug design/John G. Topliss and Yvonne C. Martin. 2. The design of enzyme inhibitors transition state analogs/R.N. Lindquist. 3. Structure absorption distribution relationships significance for drug design/Eric J. Lien. 4. The role of charge transfer processes in the action of bioactive materials/Peter H. Doukas. 5. Approaches to the rational combination of antimetabolites for cancer chemotherapy/Gerald B. Grindey Richard G. Moran and William G. Werkheiser. 6. Physicochemical quantum chemical and other theoretical techniques for the understanding of the mechanism of action of CNS agents psychoactive drugs narcotics and narcotic antagonists and anesthetics/Joyce J. Kaufman and Walter S. Koski. Subject index. Vol. VI. Preface. 1. Diphenhydramine derivatives through manipulation toward design/A.F. Harms W. Hespe W. Th.…

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Détails bibliographiques

Titre
Medicinal Chemistry : A Series of Monographs: Vol: 11: Drug Design ( Part 1 to 10 Set)
Auteur
E J Ariens
Éditeur
Academic Press for Elsevier, Noida
Année de publication
2009
État de l'article
As New
Jaquette
Jaquette
Reliure
Hardbound
Édition
New

Vedams eBooks (P) Ltd

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