Microfluidic Cell Culture Systems (Micro and Nano Technologies)

Langue : anglais

Edité par Elsevier, 2019

0128136715 / 9780128136713

Série : Livre 165 sur 393 - Micro and Nano Technologies

Vendeur : killarneybooks, Inagh, Clare, Irlandekillarneybooks

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Vendeur AbeBooks depuis 20 avril 2017

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Oversized paperback, second edition, xv + 380 pages, NOT ex-library. Signs of light wear; book is clean and bright with unmarked text, free of inscriptions and stamps, firmly bound. Straight spine. -- This is a technical manual for designing and using Organ-on-a-Chip technology. It focuses on the intersection of microfabrication and cell biology, providing the engineering blueprints needed to create miniature, functional models of human organs. Core Objectives: - Engineering 3D Environments: It explains how to move beyond flat Petri dishes to create 3D micro-environments that mimic the physical and chemical conditions inside the human body; - Disease Modelling: A major focus is the development of specific models for drug toxicity testing and disease progression, particularly for the liver and lung. - Scale-Up for Industry: It addresses the "translation" problem - how to move a delicate microfluidic device from a university lab to a mass-produced industrial tool for pharmaceutical screening. Technical Breakdown: - Micro-scale Physics: The text details how fluids behave at the micron level, focusing on laminar flow, shear stress, and nutrient delivery to living cells. - Biomaterials: It reviews the materials used to build these systems (such as PDMS and other polymers) and how to ensure they are biocompatible so they do not kill the cells they are meant to house. - Multi-Organ Systems: The book explores "Body-on-a-Chip" concepts, where multiple organ models are connected by micro-channels to simulate how a drug might move from the gut to the liver and eventually the bloodstream. It serves as a bridge for engineers who understand fluid dynamics but need to learn cell biology, and for biologists who understand disease but need the hardware to simulate it accurately without using animal models.

N° de réf. du vendeur 013026

Titre
Microfluidic Cell Culture Systems (Micro and Nano Technologies)
Auteur
Jeffrey T. Borenstein; Vishal Tandon; Sarah L. Tao; Joseph L. Charest
Éditeur
Elsevier
Année de publication
2019
État de l'article
Very Good
Reliure
Soft cover
Langue
anglais
ISBN à 10 chiffres
0128136715
ISBN à 13 chiffres
9780128136713
Édition
2nd Edition
Série
Livre 165 sur 393: Micro and Nano Technologies

killarneybooks

Inagh, Clare, Irlande

Vendeur avec une évaluation de 5 étoiles

Vendeur AbeBooks depuis 20 avril 2017

Frais d'expédition de Irlande vers Etats-Unis

Article5 à 7 jours ouvrés2 à 4 jours ouvrés
Premier articleEUR 34,84EUR 38,00
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All U.S.-bound orders are now shipped with UPS for reliable delivery. Additional customs or import fees are highly unlikely; however, please note buyers remain responsible for any duties or taxes that U.S. Customs may assess. -- Killarneybooks is a family-run bookshop based in the Republic of Ireland. We take pride in accurate listings, careful packaging, and prompt service - most orders ship within 24 hours. All books listed are in stock and ready for immediate dispatch - we are not dropshippers. Inquiries always welcome.

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professional, academic, non-fiction