Neonatal Immunity

Constantin Bona

ISBN 10: 161737492X / ISBN 13: 9781617374920

Edité par Humana Press Inc., 2010

Series: Contemporary Immunology. Num Pages: 401 pages, biography. BIC Classification: MJCM. Category: (P) Professional & Vocational. Dimension: 229 x 152 x 21. Weight in Grams: 539. . 2010. Softcover reprint of hardcover 1st ed. 2005. Paperback. . . . . Books ship from the US and Ireland. N° de réf. du vendeur V9781617374920

Synopsis :

A critical review of the classic, as wells as most recent-and quite seminal-findings concerning the phenotypic and molecular characteristics of both fetal and neonatal B and T cells, the cells that mediate antibody and cellular immune responses in newborns and infants. Dr. Bona shows how the antibody response of neonates is modulated by maternal antibodies and how, in certain cases, this can cause transient or life-threatening neonatal autoimmune disease. He also describes the characteristics of neonatal tolerance induced by foreign allo- and self-antigens, which are the basis for understanding impaired infant immune response and which provide a rationale for the development of efficient neonatal vaccines. By making clear the characteristics and differences between the immune system and the immune responses of both newborns and infants, compared to those of adults, Dr. Bona offers insights and challenging hypotheses that promise to help overcome the poor responses of neonates to various antigens.

Présentation de l'éditeur: A critical review of the classic, as wells as most recent-and quite seminal-findings concerning the phenotypic and molecular characteristics of both fetal and neonatal B and T cells, the cells that mediate antibody and cellular immune responses in newborns and infants. Dr. Bona shows how the antibody response of neonates is modulated by maternal antibodies and how, in certain cases, this can cause transient or life-threatening neonatal autoimmune disease. He also describes the characteristics of neonatal tolerance induced by foreign allo- and self-antigens, which are the basis for understanding impaired infant immune response and which provide a rationale for the development of efficient neonatal vaccines. By making clear the characteristics and differences between the immune system and the immune responses of both newborns and infants, compared to those of adults, Dr. Bona offers insights and challenging hypotheses that promise to help overcome the poor responses of neonates to various antigens.

Détails bibliographiques

Titre : Neonatal Immunity
Éditeur : Humana Press Inc.
Date d'édition : 2010
Reliure : Couverture souple
Etat : New