OSTEOPOROSIS IN OLDER PERSONS: PATHOPHYSIOLOGY AND THERAPEUTIC APPROACH. Cet article n’est pas disponible.OSTEOPOROSIS IN OLDER PERSONS: PATHOPHYSIOLOGY AND THERAPEUTIC APPROACH

Until recently, most efforts concerning osteoporosis research was mainly directed at the mechanisms of a type of osteoporosis known as post-menopausal osteoporosis. However, a new syndrome, osteoporosis in older persons, has been recognized as a new entity with its own pathophysiology and potential treatments.

This book details recent advances in the elucidation of the mechanisms involved in senile osteoporosis as well as its potential treatment, bringing an integrated approach from the bench to the clinical practice. A unique aspect of this book is its emphasis on the application of translational research in the field of osteoporosis and falls which make it useful not only to biologists but also to clinicians and epidemiologists. The chapters include tables and flowcharts and are farther complemented with color figures that show the basics of bone biology, bone phenotypes and falls prevention interventions.

Osteoporosis in Older Persons - Pathophysiology and Therapeutic Approach has the most up-to-date information about the pathophysiology and new therapeutic alternatives. Until recently most effort concerning osteoporosis research was directed mainly at the mechanisms of a type of osteoporosis known as post-menopausal osteoporosis. It was only just recently that a new syndrome, osteoporosis in older persons, was recognized as a new entity with its own pathophysiology and potential treatments. Highlights of this book include:- - Many illustrations showing the basic biological pathways involved in bone aging, as well as the potential links between aging and the changes in bone biology - Figures showing the potential therapeutic targets in bone to prevent and treat osteoporosis, complemented by a complete review on the current treatments - Descriptions of the epidemiology of osteoporotic fractures and their impact on health care costs - Coverage of fractures and their relationship with falls, including new invasive and non-invasive therapeutic approach for osteoporotic fractures - A complete review of future treatments is included explaining their biological basis as well as their potential indications Written by leading clinicians and practitioners in the field this book will be of use to those involved with aging bone research, geriatricians, gerontologists, and bone biologists, as well as offering medical trainees an understanding of the mechanisms of osteoporosis in the older person, with a practical approach to diagnosis and treatment in mind.